SCHEMBL339306

SCHEMBL339306

O=C(O)c1cc(/C=C/n2nnnc2C(F)(F)F)nn1-c1ncccc1Cl

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 4/20 0.33
TRPA1 O75762 2/20 0.33
MALT1 Q9UDY8 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL339307 1.00 TRPV1 (0.33) TRPV1TRPA1MALT1
SCHEMBL45070 0.90 MALT1 (0.35) TRPV1TRPA1MALT1
SCHEMBL339427 0.90 MALT1 (0.35) TRPV1TRPA1MALT1
SCHEMBL45475 0.86 TRPA1 (0.35) TRPV1TRPA1MALT1
SCHEMBL366582 0.85
SCHEMBL341061 0.82 TRPV1 (0.33) TRPV1TRPA1MALT1
SCHEMBL341062 0.82 TRPV1 (0.33) TRPV1TRPA1MALT1
SCHEMBL2131767 0.81 TRPV1 (0.35) TRPV1TRPA1MALT1
SCHEMBL23142280 0.77 MARS1 (0.35) TRPV1TRPA1
SCHEMBL341159 0.75 ALDH1A1 (0.33) TRPV1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2582688-B1 ANTHRANILIC ACID DIAMIDE DERIVATIVES BAYER IP GMBH (DE) 2015-10-07 EP disclosed
US-8791139-B2 Anthranilic diamide derivatives BAYER CROPSCIENCE AG (DE) 2014-07-29 US disclosed
CN-103068813-A Anthranilic acid diamide derivatives BAYER CROPSCIENCE AG 2013-04-24 CN disclosed
US-20120015980-A1 ANTHRANILIC DIAMIDE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2012-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120015980-A1 ANTHRANILIC DIAMIDE DERIVATIVES DDT, QDPR, ANTXR2 TRPV1 2761/4885TRPA1 1434/4885MALT1 4605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.