Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.56 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | AGER | Q15109 | 1/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.49 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3398555 | 0.90 | RAB9A (0.55) | CACNA1BAPBA1MAPTPOLBAGER | |
| SCHEMBL3398551 | 0.89 | POLB (0.49) | CACNA1BAPBA1MAPTPOLBAGER | |
| SCHEMBL3397270 | 0.89 | PTPN11 (0.50) | CACNA1BAPBA1POLBAGERMAPK13 | |
| SCHEMBL3393963 | 0.89 | NAMPT (0.56) | POLBTDP1KMT2AALDH1A1KDM4E | |
| SCHEMBL3393588 | 0.87 | CSNK2A2 (0.55) | MAPTPOLBMAPK13MAPK12MAPK11 | |
| SCHEMBL3394933 | 0.84 | CSNK2A2 (0.60) | MAPTPOLBRXFP1MAPK13MAPK12 | |
| SCHEMBL3397155 | 0.80 | CSNK2A2 (0.60) | POLBMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL3390828 | 0.80 | MEN1 (0.56) | MAPTPOLBRXFP1MAPK13MAPK12 | |
| SCHEMBL3397171 | 0.77 | MAPK13 (0.69) | POLBRXFP1MAPK13MAPK12MAPK11 | |
| SCHEMBL2366826 | 0.75 | TNIK (0.80) | MAPTPOLBTNIK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216795-A1 | TNIK INHIBITOR AND THE USE | YAMADA TESSHI | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216795-A1 | TNIK INHIBITOR AND THE USE | TNIK, TNNI3K, TNK1 | CACNA1B 2155/4885APBA1 3744/4885MAPT 3204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.