Sugi Predict

Sugi Predict / Compounds / SCHEMBL3393678

SCHEMBL3393678

SCHEMBL3393678

NC(=O)CCc1ccc(Cl)c(Cl)c1

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ PYGL P06737 1/20 0.57
▸ TAAR1 Q96RJ0 2/20 0.57
▸ PNMT P11086 1/20 0.57
▸ PDPK1 O15530 1/20 0.53
▸ FFAR1 O14842 1/20 0.50
▸ PLAAT3 P53816 1/20 0.50
▸ PLAAT5 Q96KN8 1/20 0.50
▸ PLAAT2 Q9NWW9 1/20 0.50
▸ PLAAT4 Q9UL19 1/20 0.50
▸ CDK8 P49336 1/20 0.49
▸ CLK4 Q9HAZ1 1/20 0.49
▸ IGF1R P08069 1/20 0.49
▸ ALOX15 P16050 1/20 0.49
▸ IDO1 P14902 4/20 0.47
▸ SIGMAR1 Q99720 3/20 0.47
▸ FDPS P14324 1/20 0.46
▸ TSHR P16473 1/20 0.46
▸ CAPN1 P07384 1/20 0.46
▸ TRPV1 Q8NER1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6078543 0.91 IGF1R (0.56) PYGLTAAR1PNMTPDPK1FFAR1
SCHEMBL28022655 0.85 CA2 (0.56) PYGLIGF1RALOX15CAPN1
SCHEMBL7330823 0.84 PYGL (0.60) PYGLTAAR1PNMTPDPK1FFAR1
SCHEMBL26937838 0.84 SLC22A12 (0.47) PYGLTAAR1PNMTPDPK1FFAR1
SCHEMBL30540321 0.84 PNMT (0.43) PYGLTAAR1PNMTPDPK1FFAR1
SCHEMBL12498436 0.84 PNMT (0.43) PYGLTAAR1PNMTPDPK1FFAR1
SCHEMBL15517814 0.84 PIK3CA (0.47) PYGLTAAR1PNMTALOX15IDO1
Hydrochloric Acid SCHEMBL15774934 0.84 CYP3A4 (0.53) PYGLTAAR1PNMTPDPK1FFAR1
SCHEMBL1303440 0.82 PYGL (0.58) PYGLTAAR1PNMTPDPK1FFAR1
SCHEMBL1206803 0.82 FFAR1 (0.69) PYGLTAAR1PNMTPDPK1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113402410-B Method for efficiently preparing 3, 4-dichlorophenyl propionamide 宁夏格瑞精细化工有限公司 2023-04-14 — — CN claimed
CN-113402410-A Method for efficiently preparing 3, 4-dichlorophenyl propionamide 宁夏格瑞精细化工有限公司 2021-09-17 — — CN claimed
US-20110053985-A1 NOVEL PIPERIDINE-4-CARBOXYLIC ACID PHENYL-ALKYL-AMIDE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS NEUROSEARCH A/S (DK) 2011-03-03 — — US claimed
EP-2245011-A1 NOVEL PIPERIDINE-4-CARBOXYLIC ACID PHENYL-ALKYL-AMIDE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS NeuroSearch A/S (DK) 2010-11-03 — — EP claimed
WO-2009090173-A1 NOVEL PIPERIDINE-4-CARBOXYLIC ACID PHENYL-ALKYL-AMIDE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS NEUROSEARCH A/S (DK) 2009-07-23 — — WO claimed
US-7563748-B2 Alcohol alkoxylate carriers for pesticide active ingredients COGNIS IP MANAGEMENT GMBH (DE) 2009-07-21 — — US claimed
EP-1633715-A1 2-(6-AMINO-PYRIDIN-3-YL)-2-HYDROXYETHYLAMINE DERIVATIVES AS BETA 2-ADRENOCEPTORS AGONISTS Pfizer Limited (GB) 2006-03-15 — — EP claimed
EP-1341774-B1 FUSED HETEROAROMATIC GLUCOKINASE ACTIVATORS HOFFMANN LA ROCHE (CH) 2006-02-01 — — EP claimed
WO-2004108676-A1 2-(6-AMINO-PYRIDIN-3-YL)-2-HYDROXYETHYLAMINE DERIVATIVES AS BETA 2-ADRENOCEPTORS AGONISTS PFIZER LIMITED (GB) 2004-12-16 — — WO claimed
CN-115181033-B Catalytic synthesis method of propanil 内蒙古莱科作物保护有限公司 2024-03-15 — — CN disclosed
WO-2024042437-A1 NOVEL SYNERGISTIC HERBICIDAL COMPOSITION COROMANDEL INTERNATIONAL LIMITED (IN) 2024-02-29 — — WO disclosed
CN-113402410-B Method for efficiently preparing 3, 4-dichlorophenyl propionamide 宁夏格瑞精细化工有限公司 2023-04-14 — — CN disclosed
CN-113402410-B Method for efficiently preparing 3, 4-dichlorophenyl propionamide 宁夏格瑞精细化工有限公司 2023-04-14 — — CN disclosed
CN-113402410-B Method for efficiently preparing 3, 4-dichlorophenyl propionamide 宁夏格瑞精细化工有限公司 2023-04-14 — — CN disclosed
US-4369186-A INSECTICIDE, MITICIDE, FUNGICIDE, AND HERBICIDE BAYER AKTIENGESELLSCHAFT (DE) 1983-01-18 — — US disclosed
US-4179277-A NEMATOCIDES, INSECTICIDES, FUNGICIDES, HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1979-12-18 — — US disclosed
US-4087272-A POSTEMERGENCE HERBICIDES BAYER AKTIENGESELLSCHAFT (DT) 1978-05-02 — — US disclosed
US-4067724-A N-(1,2,4-Triazin-5-on-4-yl)-glycines and herbicidal compositions BAYER AKTIENGESELLSCHAFT (DT) 1978-01-10 — — US disclosed
US-4058525-A 4-Amino-5-thione-1,2,4-triazines BAYER AKTIENGESELLSCHAFT (DT) 1977-11-15 — — US disclosed
US-4057418-A Sulfonylmethylamino-substituted benzoic acids and herbicidal method therewith BAYER AKTIENGESELLSCHAFT (DT) 1977-11-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110053985-A1 NOVEL PIPERIDINE-4-CARBOXYLIC ACID PHENYL-ALKYL-AMIDE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS SLC18A2, SLC6A2, SLC18A3 PYGL 3137/4885TAAR1 41/4885PNMT 15/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.