Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PYGL | P06737 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6845426 | 0.92 | ALDH1A1 (0.41) | SLC22A12FFAR1AIMP2ALDH1A1MAPT | |
| SCHEMBL27562952 | 0.86 | IAPP (0.49) | FFAR1AIMP2ALDH1A1MAPTNPSR1 | |
| SCHEMBL14461367 | 0.84 | FFAR1 (0.55) | SLC22A12FFAR1NPSR1FFAR4 | |
| SCHEMBL3393678 | 0.84 | PYGL (0.57) | FFAR1ALOX15CAPN1PYGLCDK8 | |
| SCHEMBL8534702 | 0.84 | CAPN1 (0.46) | SLC22A12FFAR1ALDH1A1ALOX15CAPN1 | |
| SCHEMBL4685210 | 0.82 | CA2 (0.47) | ALDH1A1MAPTMEN1ALOX15MAPK1 | |
| SCHEMBL28022655 | 0.81 | CA2 (0.56) | ALOX15CAPN1PYGLCYP3A4 | |
| SCHEMBL14461366 | 0.80 | RAB9A (0.48) | AIMP2ALDH1A1MAPTKDM4EPYGL | |
| SCHEMBL15517814 | 0.79 | PIK3CA (0.47) | SLC22A12ALDH1A1MAPTALOX15CAPN1 | |
| SCHEMBL26937826 | 0.79 | DAO (0.47) | SLC22A12FFAR1ALDH1A1KMT2ACAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4074701-B1 | NOVEL AMIDE DERIVATIVE USEFUL AS DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITOR, AND USE THEREOF | LG CHEMICAL LTD (KR) | 2023-12-13 | — | — | EP | disclosed |