Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL2955595 | 0.91 | — | — | |
| Potassium Ion SCHEMBL6839 | 0.89 | — | — | |
| SCHEMBL81 | 0.89 | — | — | |
| SCHEMBL2169602 | 0.89 | — | — | |
| Methyl Alcohol SCHEMBL28770132 | 0.84 | — | — | |
| SCHEMBL1190396 | 0.80 | — | — | |
| Water SCHEMBL1014000 | 0.80 | — | — | |
| SCHEMBL8696484 | 0.80 | — | — | |
| SCHEMBL5141657 | 0.80 | — | — | |
| SCHEMBL19547829 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114105862-A | Donepezil hydrochloride impurity and preparation method thereof | 浙江华海药业股份有限公司 | 2022-03-01 | — | — | CN | claimed |
| CN-105646216-A | Synthesis method of 2-fluoro-methyl 3-hydroxypropionate | 湖北工程学院 | 2016-06-08 | — | — | CN | claimed |
| WO-1998003262-A1 | AN IMPROVED PROCESS FOR THE CONVERSION OF FATTY AMIDES TO AMINES | STEPAN COMPANY (US) | 1998-01-29 | — | — | WO | claimed |
| EP-4351512-A1 | BLENDS OF N-ACYL ALANINATES AND OTHER N-ACYL AMINO ACID SURFACTANTS AND DERIVATIVES THEREOF | The Procter & Gamble Company (US) | 2024-04-17 | — | — | EP | disclosed |
| CN-114369080-B | Device and method for synthesizing ethylene carbonate or propylene carbonate | 凯瑞环保科技股份有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-114437014-B | Device and method for synthesizing ethylene carbonate or propylene carbonate | 凯瑞环保科技股份有限公司 | 2024-03-19 | — | — | CN | disclosed |
| US-20220403291-A1 | BLENDS OF N-ACYL ALANINATES AND OTHER N-ACYL AMINO ACID SURFACTANTS AND DERIVATIVES THEREOF | THE PROCTER & GAMBLE COMPANY | 2022-12-22 | — | — | US | disclosed |
| WO-2022261635-A1 | BLENDS OF N-ACYL ALANINATES AND OTHER N-ACYL AMINO ACID SURFACTANTS AND DERIVATIVES THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2022-12-15 | — | — | WO | disclosed |
| EP-3838888-B1 | TRIESTERS OF CYCLOHEXANTRIPROPIONIC ACID | EVONIK OPERATIONS GMBH (DE) | 2022-03-30 | — | — | EP | disclosed |
| CN-114105862-A | Donepezil hydrochloride impurity and preparation method thereof | 浙江华海药业股份有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-113166393-A | Method for preparing polyoxyethylene 1, 4-sorbitan fatty acid ester | 广州龙沙制药有限公司 | 2021-07-23 | — | — | CN | disclosed |
| WO-2008052769-A1 | PHENYLAMINO-SUBSTITUTED PIPERIDINE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE S.A. (ES) | 2008-05-08 | — | — | WO | disclosed |
| EP-1918281-A1 | Phenylamino-substituted piperidine compounds, their preparation and use as medicaments | Laboratorios del Dr. Esteve S.A. (ES) | 2008-05-07 | — | — | EP | disclosed |
| EP-1866278-A1 | SUBSTITUTED ARYLOXOETHYL CYCLOPROPANECARBOXAMIDE COMPOUNDS AS VR1 RECEPTOR ANTAGONISTS | Pfizer, Inc. (US) | 2007-12-19 | — | — | EP | disclosed |
| EP-1861359-A1 | N-(N-SULFONYLAMINOMETHYL)CYCLOPROPANECARBOXAMIDE DERIVATIVES USEFUL FOR THE TREATMENT OF PAIN | Pfizer, Inc. (US) | 2007-12-05 | — | — | EP | disclosed |
| WO-2007133637-A2 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | RENOVIS, INC. (US) | 2007-11-22 | — | — | WO | disclosed |
| WO-2006097817-A9 | N- (N-SULFONYLAMINOMETHYL) CYCLOPROPANECARBOXAMIDE DERIVATIVES USEFUL FOR THE TREATMENT OF PAIN | PFIZER JAPAN INC (JP) | 2006-12-07 | — | — | WO | disclosed |
| WO-2006103503-A1 | SUBSTITUTED ARYLOXOETHYL CYCLOPROPANECARBOXAMIDE COMPOUNDS AS VR1 RECEPTOR ANTAGONISTS | PFIZER JAPAN INC. (JP) | 2006-10-05 | — | — | WO | disclosed |
| WO-2006097817-A1 | N- (N-SULFONYLAMINOMETHYL) CYCLOPROPANECARBOXAMIDE DERIVATIVES USEFUL FOR THE TREATMENT OF PAIN | PFIZER JAPAN INC. (JP) | 2006-09-21 | — | — | WO | disclosed |
| US-20060211741-A1 | Substituted sulfonylaminoarylmethyl cyclopropanecarboxamide as VR1 receptor antagonists | PFIZER, INC. | 2006-09-21 | — | — | US | disclosed |