SCHEMBL3393989

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3391932	0.84	POLB (0.49)	MEN1KMT2ACACNA2D1CACNA1BCACNB1
	SCHEMBL3393165	0.82	CHRM2 (0.53)	CACNA2D1CACNA1BCACNB1CACNA1CHTR2A
	SCHEMBL3394400	0.79	HTR2A (0.64)	CACNA2D1CACNA1BCACNB1CACNA1CHTR2A
	SCHEMBL13108350	0.72	HSD11B1 (0.60)	MEN1KMT2ADRD3DRD2DRD4
	SCHEMBL3396087	0.72	CACNA2D1 (0.55)	MEN1KMT2ACACNA2D1CACNA1BCACNB1
	SCHEMBL7084349	0.70	CACNA2D1 (0.47)	MEN1KMT2ACACNA2D1CACNA1BCACNB1
	SCHEMBL22475158	0.69	MEN1 (0.50)	MEN1KMT2ACACNA2D1CACNA1BCACNB1
	SCHEMBL2606127	0.68	QDPR (0.55)	HTR2AHTR2CDRD3DRD2
	SCHEMBL4749261	0.67	MEN1 (0.57)	MEN1KMT2AHTR2ADRD3DRD2
	SCHEMBL9673190	0.67	CHRM1 (0.82)	HTR2AHTR2CHTR7CYP2D6CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.