Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL314697 | 1.00 | ABL1 (0.43) | ABL1PDE10ACHEK1DHODHAXL | |
| SCHEMBL315015 | 0.89 | ABL1 (0.36) | ABL1PDE10ADHODHHSP90AA1CHRNB4 | |
| SCHEMBL3400440 | 0.89 | ABL1 (0.36) | ABL1PDE10ADHODHHSP90AA1CHRNB4 | |
| SCHEMBL2412528 | 0.89 | ABL1 (0.35) | ABL1PDE10ADHODHHDAC6FFAR4 | |
| SCHEMBL2412530 | 0.89 | ABL1 (0.35) | ABL1PDE10ADHODHHDAC6FFAR4 | |
| SCHEMBL3400655 | 0.88 | CHRNB2 (0.36) | ABL1PDE10A | |
| SCHEMBL315735 | 0.88 | CHRNB2 (0.36) | ABL1PDE10A | |
| SCHEMBL3395741 | 0.88 | ABL1 (0.32) | ABL1PDE10ADHODHCHRNB4CHRNA3 | |
| SCHEMBL314759 | 0.88 | ABL1 (0.32) | ABL1PDE10ADHODHCHRNB4CHRNA3 | |
| SCHEMBL314162 | 0.85 | DGAT2 (0.32) | DGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066683-B1 | DERIVATIVES OF 5-THIOXYLOPYRANOSE AND USE OF SAME FOR TREATMENT | FOURNIER LAB SA (FR) | 2010-11-03 | — | — | EP | disclosed |