Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL315735 | 1.00 | CHRNB2 (0.36) | CHRNB2CHRNA6CYP11B2CYP11B1ABL1 | |
| SCHEMBL3400440 | 0.92 | ABL1 (0.36) | CHRNB2CYP11B2ABL1PDE10A | |
| SCHEMBL315015 | 0.92 | ABL1 (0.36) | CHRNB2CYP11B2ABL1PDE10A | |
| SCHEMBL3395741 | 0.89 | ABL1 (0.32) | CHRNB2CYP11B2ABL1PDE10A | |
| SCHEMBL314759 | 0.89 | ABL1 (0.32) | CHRNB2CYP11B2ABL1PDE10A | |
| SCHEMBL2415462 | 0.89 | PRMT5 (0.36) | GSK3BGRM5 | |
| SCHEMBL2415464 | 0.89 | PRMT5 (0.36) | GSK3BGRM5 | |
| SCHEMBL3395247 | 0.88 | ABL1 (0.43) | ABL1PDE10A | |
| SCHEMBL314697 | 0.88 | ABL1 (0.43) | ABL1PDE10A | |
| SCHEMBL314162 | 0.86 | DGAT2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066683-B1 | DERIVATIVES OF 5-THIOXYLOPYRANOSE AND USE OF SAME FOR TREATMENT | FOURNIER LAB SA (FR) | 2010-11-03 | — | — | EP | disclosed |