Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | PIP4K2A | P48426 | 2/20 | 0.30 |
| ▸ | PIP4K2C | Q8TBX8 | 2/20 | 0.30 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.30 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL314759 | 1.00 | ABL1 (0.32) | ABL1CTSACYP11B2DHODHPIP4K2A | |
| SCHEMBL3400440 | 0.90 | ABL1 (0.36) | ABL1CYP11B2DHODHPDE10ACHRNB1 | |
| SCHEMBL315015 | 0.90 | ABL1 (0.36) | ABL1CYP11B2DHODHPDE10ACHRNB1 | |
| SCHEMBL315735 | 0.89 | CHRNB2 (0.36) | ABL1CYP11B2PDE10ACHRNB2 | |
| SCHEMBL3400655 | 0.89 | CHRNB2 (0.36) | ABL1CYP11B2PDE10ACHRNB2 | |
| SCHEMBL2409949 | 0.89 | RXFP1 (0.36) | CTSADHODH | |
| SCHEMBL2409951 | 0.89 | RXFP1 (0.36) | CTSADHODH | |
| SCHEMBL3395247 | 0.88 | ABL1 (0.43) | ABL1DHODHPDE10ACHRNB4CHRNA3 | |
| SCHEMBL314697 | 0.88 | ABL1 (0.43) | ABL1DHODHPDE10ACHRNB4CHRNA3 | |
| SCHEMBL3398348 | 0.87 | CYP11B2 (0.33) | CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066683-B1 | DERIVATIVES OF 5-THIOXYLOPYRANOSE AND USE OF SAME FOR TREATMENT | FOURNIER LAB SA (FR) | 2010-11-03 | — | — | EP | disclosed |