Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK6 | P43250 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 4/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.39 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13426417 | 0.85 | CACNA1H (0.39) | GRK6PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3395630 | 0.79 | HDAC6 (0.44) | MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL13425946 | 0.71 | IDO1 (0.35) | — | |
| SCHEMBL3396698 | 0.71 | GABRA1 (0.44) | PHGDHMAPK1MEN1ALDH1A1RAB9A | |
| SCHEMBL3394902 | 0.71 | GSK3B (0.39) | PHGDHCASP1 | |
| SCHEMBL13425447 | 0.71 | SMPD3 (0.40) | GRK6PHGDHKDM1AGAASMN1; SMN2 | |
| SCHEMBL14982263 | 0.71 | PKM (0.46) | GRK6PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL13425931 | 0.70 | KMO (0.38) | MAPTNPSR1GPR55CASP1 | |
| SCHEMBL14982289 | 0.70 | PDE4A (0.53) | GRK6PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14982211 | 0.69 | PKM (0.47) | GRK6PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |