Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5341216 | 0.88 | KIF11 (1.00) | KIF11HSD17B10SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL10113145 | 0.88 | HSD17B10 (0.67) | KIF11HSD17B10MEN1KMT2ALMNA | |
| SCHEMBL3397866 | 0.82 | PKM (0.80) | KIF11SMN1; SMN2ALDH1A1PKMADORA2B | |
| SCHEMBL3399033 | 0.82 | KIF11 (0.79) | KIF11HSD17B10SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL3397010 | 0.80 | KIF11 (0.76) | KIF11HSD17B10MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5339172 | 0.80 | KIF11 (0.65) | KIF11HSD17B10MAPK1POLBPKM | |
| SCHEMBL5352815 | 0.80 | KIF11 (0.65) | KIF11HSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL10113180 | 0.79 | HSD17B10 (0.77) | HSD17B10MEN1KMT2APOLBADORA2B | |
| SCHEMBL13425501 | 0.78 | KIF11 (0.73) | KIF11HSD17B10SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL15196473 | 0.78 | KIF11 (0.73) | KIF11HSD17B10MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |