Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | GUSB | P08236 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5341216 | 0.89 | KIF11 (1.00) | KIF11SMN1; SMN2NPSR1ALDH1A1ALOX15 | |
| SCHEMBL15196473 | 0.85 | KIF11 (0.73) | KIF11SMN1; SMN2NPSR1ALDH1A1ALOX15 | |
| SCHEMBL3397866 | 0.84 | PKM (0.80) | KIF11SMN1; SMN2ALDH1A1PKMGAA | |
| SCHEMBL3397010 | 0.83 | KIF11 (0.76) | KIF11SMN1; SMN2NPSR1ALDH1A1ALOX15 | |
| SCHEMBL3395980 | 0.82 | KIF11 (0.78) | KIF11SMN1; SMN2NPSR1ALDH1A1ALOX15 | |
| SCHEMBL13425501 | 0.81 | KIF11 (0.73) | KIF11SMN1; SMN2NPSR1ALDH1A1ALOX15 | |
| SCHEMBL5173918 | 0.80 | DHFR (0.74) | KIF11SMN1; SMN2NPSR1ALDH1A1ALOX15 | |
| SCHEMBL3398149 | 0.80 | KIF11 (0.71) | KIF11SMN1; SMN2NPSR1ALDH1A1ALOX15 | |
| SCHEMBL31705192 | 0.78 | KIF11 (0.80) | KIF11SMN1; SMN2ALDH1A1MAPK1HSD17B10 | |
| SCHEMBL5340534 | 0.78 | KIF11 (0.80) | KIF11SMN1; SMN2ALDH1A1MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |