SCHEMBL4179918

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8002247	0.86	REV1 (0.62)	GAAREV1MAPTALDH1A1MAPK1
	SCHEMBL5114345	0.85	REV1 (0.65)	GAAREV1MAPTALDH1A1MAPK1
	SCHEMBL6698451	0.85	MAPT (0.59)	GAAMAPTALDH1A1MAPK1LMNA
	SCHEMBL10963122	0.85	ME2 (0.58)	GAAMAPTALDH1A1LMNAMEN1
	SCHEMBL6698448	0.83	ALDH1A1 (0.61)	MAPTALDH1A1HTTCYP1A2CYP3A4
	SCHEMBL4400390	0.83	SMN1; SMN2 (0.66)	MAPTALDH1A1MAPK1LMNAHTT
	SCHEMBL4403555	0.83	CA1 (0.56)	GAAMAPTALDH1A1LMNAHTT
	SCHEMBL3396020	0.83	REV1 (0.59)	GAAREV1MAPTALDH1A1MAPK1
	SCHEMBL8576314	0.83	REV1 (0.59)	GAAREV1MAPTALDH1A1MAPK1
	Hydrochloric Acid SCHEMBL1373922	0.83	REV1 (0.63)	GAAREV1MAPTALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.