SCHEMBL3396087

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23293565	0.90	OPRM1 (0.48)	CACNA2D1CACNA1BCACNB1CACNA1COPRM1
	SCHEMBL493568	0.89	CACNA2D1 (0.52)	CACNA2D1CACNA1BCACNB1CACNA1COPRM1
	SCHEMBL23802612	0.87	OPRM1 (0.52)	CACNA2D1CACNA1BCACNB1CACNA1COPRM1
	SCHEMBL3391989	0.86	CACNA2D1 (0.55)	CACNA2D1CACNA1BCACNB1CACNA1COPRM1
	SCHEMBL30330203	0.85	OPRM1 (0.57)	CACNA2D1CACNA1BCACNB1CACNA1COPRM1
	SCHEMBL3395013	0.85	CACNA2D1 (0.57)	CACNA2D1CACNA1BCACNB1CACNA1COPRM1
	SCHEMBL30330200	0.77	ACHE (0.43)	CACNA2D1CACNA1BCACNB1CACNA1COPRM1
	Trifluoroacetic Acid SCHEMBL23293327	0.77	OPRD1 (0.52)	CACNA2D1CACNA1BCACNB1CACNA1COPRM1
	Methylpiperazine SCHEMBL28078163	0.74	SIGMAR1 (0.47)	SLC6A2SLC6A4SIGMAR1SLC6A3KCNH2
	SCHEMBL493178	0.74	CACNA2D1 (0.61)	CACNA2D1CACNA1BCACNB1CACNA1COPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.