Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7030462 | 0.88 | MAPT (0.33) | GABRA1GABRB2ALDH1A1GAAMAPT | |
| SCHEMBL28729836 | 0.78 | GABRA1 (0.35) | GABRA1GABRB2ALDH1A1HTTGAA | |
| SCHEMBL8770575 | 0.73 | ADRA2A (0.35) | GABRA1GABRB2MAPTKMT2AMEN1 | |
| SCHEMBL1686677 | 0.69 | GABRA1 (0.46) | GABRA1GABRB2ALDH1A1GAAMAPT | |
| SCHEMBL1686693 | 0.69 | GABRA1 (0.46) | GABRA1GABRB2ALDH1A1GAAMAPT | |
| SCHEMBL8770587 | 0.67 | GABRA1 (0.40) | GABRA1GABRB2ALDH1A1HTTGAA | |
| SCHEMBL12441757 | 0.66 | GABRA1 (0.42) | GABRA1GABRB2MAPTNPSR1L3MBTL1 | |
| SCHEMBL1562731 | 0.66 | GABRA1 (0.38) | GABRA1GABRB2MAPTNPSR1L3MBTL1 | |
| SCHEMBL669702 | 0.66 | GABRA1 (0.38) | GABRA1GABRB2MAPTNPSR1L3MBTL1 | |
| SCHEMBL9617750 | 0.65 | GABRA1 (0.41) | GABRA1GABRB2MAPTNPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247630-A1 | MODIFIED CHROMIUM-BASED CATALYSTS AND POLYMERIZATION PROCESSES FOR USING THE SAME | Univation Technologies, LLC (US) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009108174-A1 | MODIFIED CHROMIUM-BASED CATALYSTS AND POLYMERIZATION PROCESSES FOR USING THE SAME | UNIVATION TECHNOLOGIES, LLC (US) | 2009-09-03 | — | — | WO | disclosed |