Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.61 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.61 |
| ▸ | CDK2 | P24941 | 1/20 | 0.58 |
| ▸ | DPP4 | P27487 | 1/20 | 0.58 |
| ▸ | CDK1 | P06493 | 1/20 | 0.57 |
| ▸ | BRAF | P15056 | 10/20 | 0.56 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.55 |
| ▸ | PRKACA | P17612 | 3/20 | 0.54 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.53 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29672206 | 0.84 | PDPK1 (0.59) | PDPK1GDACDK2DPP4CDK1 | |
| SCHEMBL164700 | 0.84 | XDH (0.65) | PDPK1GDACDK2DPP4CDK1 | |
| SCHEMBL2938906 | 0.84 | PDPK1 (0.59) | PDPK1GDACDK2DPP4CDK1 | |
| SCHEMBL332978 | 0.80 | BRAF (0.60) | PDPK1GDACDK2DPP4CDK1 | |
| SCHEMBL27820320 | 0.80 | PDPK1 (0.54) | PDPK1GDACDK2DPP4CDK1 | |
| SCHEMBL16147021 | 0.80 | CDK1 (0.63) | PDPK1GDACDK2DPP4CDK1 | |
| SCHEMBL10838746 | 0.78 | NUDT1 (0.67) | PDPK1GDACDK2DPP4CDK1 | |
| SCHEMBL133157 | 0.78 | LMNA (0.54) | PDPK1GDACDK2DPP4CDK1 | |
| SCHEMBL5355413 | 0.77 | BRAF (0.73) | CDK1BRAFNUDT1EIF2AK2 | |
| SCHEMBL16146643 | 0.77 | MGMT (0.55) | PDPK1GDACDK2DPP4CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019227847-A1 | CHITOSAN-BASED IONIC CONDUCTIVE MATERIAL CONTAINING PURINE STRUCTURE AND PREPARATION METHOD THEREOF | 华南理工大学 (CN) | 2019-12-05 | — | — | WO | claimed |
| US-11254982-B2 | Osmiumtetroxide-based conversion of RNA and DNA containing thiolated nucleotides | UNIVERSITY OF INNSBRUCK (AT) | 2022-02-22 | — | — | US | disclosed |
| US-20200048700-A1 | OSMIUMTETROXIDE-BASED CONVERSION OF RNA AND DNA CONTAINING THIOLATED NUCLEOTIDES | UNIVERSITY OF INNSBRUCK (AT) | 2020-02-13 | — | — | US | disclosed |
| CN-109036623-A | A kind of cellulose base ion conductive material of purine-containing structure and preparation method thereof | 华南理工大学 | 2018-12-18 | — | — | CN | disclosed |
| EP-2249874-A1 | METHODS AND MEANS FOR TREATING DNA REPEAT INSTABILITY ASSOCIATED GENETIC DISORDERS | ProSensa Holding BV (NL) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009099326-A1 | METHODS AND MEANS FOR TREATING DNA REPEAT INSTABILITY ASSOCIATED GENETIC DISORDERS | PROSENSA HOLDING BV (NL) | 2009-08-13 | — | — | WO | disclosed |