SCHEMBL164700

SCHEMBL164700

CNc1nc(N)nc2nc[nH]c12

nearest known ligand 0.65

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.65
PDPK1 O15530 1/20 0.59
GDA Q9Y2T3 1/20 0.59
BRAF P15056 9/20 0.57
CDK1 P06493 2/20 0.56
CDK2 P24941 2/20 0.56
DPP4 P27487 1/20 0.56
MAP3K5 Q99683 1/20 0.56
NUDT1 P36639 1/20 0.54
PRKACA P17612 2/20 0.52
CCNB1 P14635 1/20 0.51
CCNA2 P20248 1/20 0.51
CCNA1 P78396 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3396378 0.84 PDPK1 (0.61) PDPK1GDABRAFCDK1CDK2
SCHEMBL29672206 0.82 PDPK1 (0.59) PDPK1GDABRAFCDK1CDK2
SCHEMBL2938906 0.82 PDPK1 (0.59) PDPK1GDABRAFCDK1CDK2
SCHEMBL16147021 0.81 CDK1 (0.63) PDPK1GDABRAFCDK1CDK2
SCHEMBL332978 0.81 BRAF (0.60) PDPK1GDABRAFCDK1CDK2
SCHEMBL30523428 0.80 XDH (0.67) XDHPDPK1GDABRAF
SCHEMBL20565 0.80 XDH (0.67) XDHPDPK1GDABRAF
SCHEMBL11876697 0.80 XDH (0.67) XDHBRAFCDK1CDK2CCNB1
SCHEMBL28457685 0.79 BRAF (0.54) PDPK1GDABRAFCDK1CDK2
SCHEMBL16146643 0.79 MGMT (0.55) PDPK1GDABRAFCDK1CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1385 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2026-05-28 US claimed
US-20250297329-A1 DETECTING BABESIA SPECIES NUCLEIC ACID IN A SAMPLE GEN PROBE INC (US) 2025-09-25 US claimed
WO-2025024123-A1 NOVEL CITICOLINE DERIVATIVES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-01-30 WO claimed
US-20240139325-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2024-05-02 US claimed
EP-4045504-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS Ai-biopharma (FR) 2022-08-24 EP claimed
CN-114901657-A Antiviral and liver-targeting drugs 人工智能生物制药公司 2022-08-12 CN claimed
WO-2021074443-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2021-04-22 WO claimed
US-20140303112-A1 Method for treating disease or condition susceptible to amelioration by AMPK activators and compounds of formula which are useful to activate AMP-activated protein kinase (AMPK) ENERGENESIS BIOMEDICAL CO., LTD (TW) 2014-10-09 US claimed
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2026-05-28 US disclosed
US-12630820-B2 Compositions and methods for immunotherapy INTELLIA THERAPEUTICS, INC. (US) 2026-05-19 US disclosed
US-12630891-B2 Compositions and methods for detecting or quantifying hepatitis B virus GEN-PROBE INCORPORATED (US) 2026-05-19 US disclosed
US-20260132408-A1 COMPOSITIONS AND METHODS FOR TRANSGENE EXPRESSION FROM AN ALBUMIN LOCUS INTELLIA THERAPEUTICS INC (US) 2026-05-14 US disclosed
US-20260132391-A1 Polynucleotides, Compositions, and Methods for Genome Editing INTELLIA THERAPEUTICS, INC. (US) 2026-05-14 US disclosed
US-20260125690-A1 COMPOSITIONS AND METHODS FOR TREATING ALPHA-1 ANTITRYPSIN DEFICIENCY INTELLIA THERAPEUTICS INC (US) 2026-05-07 US disclosed
EP-0286425-B1 Therapeutic nucleosides WELLCOME FOUND (GB) 1995-01-11 EP disclosed
US-5185437-A 6-substituted 2',3'-dideoxypurine nucleosides; treatment for human immunodeficiency virus and heptatis b virus BURROUGHS WELLCOME CO. (US) 1993-02-09 US disclosed
US-5068320-A 2-amino-6-(cyclopropylamino)purine-9-β-D-2',3'-dideoxyribofuranoside and its pharmaceutically acceptable salts BURROUGHS WELLCOME CO. (US) 1991-11-26 US disclosed
EP-0421819-A1 Therapeutic nucleosides THE WELLCOME FOUNDATION LIMITED (GB) 1991-04-10 EP disclosed
EP-0417999-A1 Antiviral compounds THE WELLCOME FOUNDATION LIMITED (GB) 1991-03-20 EP disclosed
EP-0286425-A2 Therapeutic nucleosides THE WELLCOME FOUNDATION LIMITED (GB) 1988-10-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132391-A1 Polynucleotides, Compositions, and Methods for Genome Editing UPF1, RNGTT, NSUN2 XDH 192/4885PDPK1 4351/4885GDA 120/4885
US-20260132408-A1 COMPOSITIONS AND METHODS FOR TRANSGENE EXPRESSION FROM AN ALBUMIN LOCUS METTL16, RNGTT, TRMT1L XDH 1692/4885PDPK1 4859/4885GDA 605/4885
US-20140303112-A1 Method for treating disease or condition susceptible to amelioration by AMPK activators and compounds of formula which are useful to activate AMP-activated protein kinase (AMPK) PRKAG2, PRKAB2, PRKAG1 XDH 253/4885PDPK1 281/4885GDA 1170/4885
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS HAVCR2, NR1H4, NR1H3 XDH 2096/4885PDPK1 4288/4885GDA 4177/4885
US-20260125690-A1 COMPOSITIONS AND METHODS FOR TREATING ALPHA-1 ANTITRYPSIN DEFICIENCY SERPINA2, SERPINH1, SERPINE1 XDH 55/4885PDPK1 4664/4885GDA 1618/4885
US-12630891-B2 Compositions and methods for detecting or quantifying hepatitis B virus UPF1, HLA-B, ADAR XDH 937/4885PDPK1 4735/4885GDA 583/4885
US-12630820-B2 Compositions and methods for immunotherapy SPOUT1, HAVCR2, STING1 XDH 2928/4885PDPK1 4702/4885GDA 1477/4885
US-20240139325-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS SLC10A1, HAVCR2, HDGF XDH 989/4885PDPK1 1722/4885GDA 1110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.