Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29655556 | 0.75 | KMT2A (0.40) | ALDH1A1KDM4ELMNATSHR | |
| SCHEMBL5189056 | 0.75 | KMT2A (0.40) | ALDH1A1KDM4ELMNATSHR | |
| SCHEMBL11959493 | 0.74 | GPR3 (0.55) | ALDH1A1ATMKDM4EGPR3 | |
| SCHEMBL9851534 | 0.73 | ATM (0.42) | ALDH1A1ATMKDM4EHSD17B10HPGD | |
| SCHEMBL25209855 | 0.72 | ERCC1 (0.44) | ALDH1A1KDM4EERCC1FEN1ERCC4 | |
| SCHEMBL23002860 | 0.69 | KDM4E (0.39) | ALDH1A1ATMKDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL30410617 | 0.67 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2HPGDMAPK14 | |
| SCHEMBL28863436 | 0.67 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2HPGDMAPK14 | |
| SCHEMBL1382913 | 0.65 | PARP1 (0.42) | ALDH1A1KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL29642546 | 0.65 | HSD17B10 (0.39) | ALDH1A1KDM4EHSD17B10SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |