Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5189056 | 1.00 | KMT2A (0.40) | KMT2APOLBTHRBL3MBTL1ALDH1A1 | |
| SCHEMBL23002860 | 0.84 | KDM4E (0.39) | KMT2APOLBL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL28200995 | 0.80 | TSHR (0.52) | KMT2APOLBL3MBTL1KDM4ETSHR | |
| SCHEMBL3677753 | 0.80 | POLB (0.44) | KMT2APOLBTHRBL3MBTL1ALDH1A1 | |
| SCHEMBL28338814 | 0.80 | EGFR (0.39) | KMT2APOLBTHRBL3MBTL1ALDH1A1 | |
| SCHEMBL28207998 | 0.80 | KDM4E (0.49) | KMT2APOLBTHRBL3MBTL1ALDH1A1 | |
| SCHEMBL3396642 | 0.75 | ALDH1A1 (0.37) | ALDH1A1KDM4ETSHRLMNA | |
| SCHEMBL17423697 | 0.74 | EGFR (0.47) | KMT2APOLBALDH1A1GLAKDM4E | |
| Butyric Acid SCHEMBL9251503 | 0.70 | FABP4 (0.45) | ALDH1A1KDM4ETSHRFABP3FABP4 | |
| SCHEMBL11959493 | 0.70 | GPR3 (0.55) | KMT2APOLBL3MBTL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114524821-A | Novel spiropyrrolidine derived antiviral drugs | 英安塔制药有限公司 | 2022-05-24 | — | — | CN | disclosed |