Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 4/20 | 0.39 |
| ▸ | GLA | P06280 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3396642 | 0.73 | ALDH1A1 (0.37) | ATMALDH1A1HTTHPGDHSD17B10 | |
| SCHEMBL11959493 | 0.72 | GPR3 (0.55) | ATMALDH1A1CYP2C19KDM4EGAA | |
| SCHEMBL16835443 | 0.71 | ALDH1A1 (0.45) | ATMALDH1A1HTTHPGDCYP2C19 | |
| Butyric Acid SCHEMBL9251503 | 0.70 | FABP4 (0.45) | ALDH1A1HSD17B10KDM4E | |
| SCHEMBL17423697 | 0.69 | EGFR (0.47) | ALDH1A1GLAHPGDCYP2C19HSD17B10 | |
| SCHEMBL5189056 | 0.69 | KMT2A (0.40) | ALDH1A1P2RX4GLAKDM4EL3MBTL1 | |
| SCHEMBL29655556 | 0.69 | KMT2A (0.40) | ALDH1A1P2RX4GLAKDM4EL3MBTL1 | |
| SCHEMBL18614818 | 0.68 | EGFR (0.49) | ALDH1A1HTTHPGDKDM4EL3MBTL1 | |
| SCHEMBL25209855 | 0.67 | ERCC1 (0.44) | ALDH1A1HTTHSD17B10KDM4EGAA | |
| SCHEMBL23002860 | 0.64 | KDM4E (0.39) | ATMALDH1A1HTTHPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424802-A2 | Tricyclic quinoline antineoplastic agents | ABBOTT LABORATORIES (US) | 1991-05-02 | — | — | EP | disclosed |