Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.85 |
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | MAPT | P10636 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | PKM | P14618 | 1/20 | 0.70 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.68 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.67 |
| ▸ | IL1RN | P18510 | 1/20 | 0.63 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.63 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
| ▸ | PPIA | P62937 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25132396 | 0.92 | ALDH1A1 (0.74) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL15840711 | 0.92 | ALDH1A1 (0.74) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL15840813 | 0.89 | ALDH1A1 (0.69) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL15840815 | 0.89 | ALDH1A1 (0.76) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL15840632 | 0.87 | ALDH1A1 (0.74) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL15840806 | 0.87 | ALDH1A1 (0.67) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL8694831 | 0.87 | ALDH1A1 (0.71) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL12472927 | 0.87 | LMNA (1.00) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL17066704 | 0.85 | GPR55 (0.86) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL15840640 | 0.85 | MAPT (0.76) | ALDH1A1LMNAMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113388083-B | Covalently-linked polyurethane/cerium oxide composite material and preparation method thereof | 丽水学院 | 2022-07-12 | — | — | CN | claimed |
| CN-114650835-A | Medicine for efficiently killing drug-resistant disease bacteria and application of medicine in inhibition of drug-resistant disease bacteria | 中国海洋大学 | 2022-06-21 | — | — | CN | claimed |
| CN-216747872-U | Special test pencil of high-voltage electronic fence | 云南电网有限责任公司楚雄供电局 | 2022-06-14 | — | — | CN | claimed |
| US-20250345369-A1 | ENGINEERED IMMUNOSTIMULATORY BACTERIAL STRAINS AND USES THEREOF | ACTYM THERAPEUTICS INC (US) | 2025-11-13 | — | — | US | disclosed |
| US-12357661-B2 | Engineered immunostimulatory bacterial strains and uses thereof | Actym Therapeutics, Inc. (US) | 2025-07-15 | — | — | US | disclosed |
| US-12226439-B2 | Engineered immunostimulatory bacterial strains and uses thereof | Actym Therapeutics, Inc. (US) | 2025-02-18 | — | — | US | disclosed |
| US-12201653-B2 | Engineered immunostimulatory bacterial strains and uses thereof | Actym Therapeutics, Inc. (US) | 2025-01-21 | — | — | US | disclosed |
| CN-221426813-U | ACCG.4 nuclear testing system clamping piece testing device | 成都思鸿维科技有限责任公司 | 2024-07-26 | — | — | CN | disclosed |
| US-12024709-B2 | Immunostimulatory bacteria engineered to colonize tumors, tumor-resident immune cells, and the tumor microenvironment | Actym Therapeutics, Inc. (US) | 2024-07-02 | — | — | US | disclosed |
| CN-118147029-A | Engineered immunostimulatory bacterial strains and uses thereof | 阿克蒂姆治疗有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-112673092-B | Engineered immunostimulatory bacterial strains and uses thereof | 阿克蒂姆治疗有限公司 | 2024-03-29 | — | — | CN | disclosed |
| US-20100058490-A1 | Gene Silencing Methods | COMMONWEALTH SCHIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 2010-03-04 | — | — | US | disclosed |
| US-20100048573-A1 | Methods of Inhibiting Bacterial Virulence and Compounds Relating Thereto | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2010-02-25 | — | — | US | disclosed |
| US-20100048573-A1 | Methods of Inhibiting Bacterial Virulence and Compounds Relating Thereto | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2010-02-25 | — | — | US | disclosed |
| US-20100048573-A1 | Methods of Inhibiting Bacterial Virulence and Compounds Relating Thereto | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2010-02-25 | — | — | US | disclosed |
| WO-2009088549-A2 | METHODS OF INHIBITING BACTERIAL VIRULENCE AND COMPOUNDS RELATING THERETO | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2009-07-16 | — | — | WO | disclosed |
| WO-2009088549-A2 | METHODS OF INHIBITING BACTERIAL VIRULENCE AND COMPOUNDS RELATING THERETO | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2009-07-16 | — | — | WO | disclosed |
| EP-2018420-A4 | IMPROVED GENE SILENCING METHODS | COMMW SCIENT IND RES ORG (AU) | 2009-06-24 | — | — | EP | disclosed |
| EP-2018420-A1 | IMPROVED GENE SILENCING METHODS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007128052-A1 | IMPROVED GENE SILENCING METHODS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2007-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048573-A1 | Methods of Inhibiting Bacterial Virulence and Compounds Relating Thereto | MMP8, SLC11A2, NFKBIA | ALDH1A1 3892/4885LMNA 4233/4885MAPT 4581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.