SCHEMBL28249448

SCHEMBL28249448

O=C(OC(c1ccccc1)(c1ccccc1)c1ccccc1)c1cccc(O)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA6 P23280 1/20 0.52
CA9 Q16790 1/20 0.52
RAB9A P51151 2/20 0.50
NPC1 O15118 1/20 0.50
PARP1 P09874 1/20 0.46
KDM4E B2RXH2 3/20 0.43
EGLN2 Q96KS0 1/20 0.43
SLC2A1 P11166 1/20 0.43
SLC2A4 P14672 1/20 0.43
ESR1 P03372 4/20 0.42
ESR2 Q92731 4/20 0.42
ALDH1A1 P00352 2/20 0.42
FASN P49327 1/20 0.41
ADRB2 P07550 1/20 0.41
ADRB1 P08588 1/20 0.41
ADRB3 P13945 1/20 0.41
P4HB P07237 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27480443 0.85 AKR1C3 (0.47) CA12CA1CA2CA6CA9
SCHEMBL3396959 0.84 LMNA (0.54) ALDH1A1LMNAPOLBMAPTMAPK1
SCHEMBL27653343 0.78 GSK3B (0.48)
SCHEMBL68806 0.77 ESR1 (0.53) CA12CA1CA2CA6CA9
SCHEMBL27925309 0.75 CDC25B (0.53) RAB9AKDM4EESR1ESR2ALDH1A1
SCHEMBL28440522 0.74 CA12 (0.61) CA12CA1CA2CA6CA9
SCHEMBL1877874 0.74 ESR1 (0.66) CA12CA1CA2CA6CA9
SCHEMBL6661362 0.72 PARP1 (0.63) CA12CA1CA2CA6CA9
SCHEMBL29905085 0.72 SLC2A1 (0.69) CA12CA1CA2CA6CA9
SCHEMBL56565 0.71 RAB9A (0.82) CA12CA1CA2CA6CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108635361-A A kind of rare flower extract and its active constituent and separation method with anti-inflammatory activity 扬州大学 2018-10-12 CN claimed
CN-108635361-A A kind of rare flower extract and its active constituent and separation method with anti-inflammatory activity 扬州大学 2018-10-12 CN disclosed