SCHEMBL3397079

SCHEMBL3397079

CCO[Si](OCC)(OCC)C(C)c1ccc(C)cc1

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 1/20 0.34
ACHE P22303 3/20 0.34
TDP1 Q9NUW8 1/20 0.32
STAT3 P40763 1/20 0.32
CYP19A1 P11511 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
SLC6A3 Q01959 1/20 0.31
ALDH1A1 P00352 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
LMNA P02545 1/20 0.31
SLC5A1 P13866 1/20 0.31
SLC5A2 P31639 1/20 0.31
ALOX5 P09917 1/20 0.31
FFAR1 O14842 1/20 0.31
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL574403 0.92 ESR1 (0.33) TDP1SLC6A3ALDH1A1LMNA
SCHEMBL27135638 0.86 PTGS2 (0.36) TDP1SLC6A3LMNA
SCHEMBL28418566 0.84 ESR1 (0.47) TDP1SLC6A3LMNA
SCHEMBL27849330 0.82 GAA (0.36) MEN1KMT2ASLC6A3ALDH1A1ALOX5
SCHEMBL27849347 0.82 CYP1A2 (0.32)
SCHEMBL928450 0.82
SCHEMBL927589 0.82 LMNA (0.32) TDP1SLC6A3LMNA
SCHEMBL926681 0.82 TSHR (0.33) TDP1
SCHEMBL929186 0.82 TSHR (0.31) TDP1
SCHEMBL574617 0.82 TAAR1 (0.39) ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101641226-B Rubber composition, method of making the same, and articles made therefrom MOMENTIVE PERFORMANCE MAT INC 2013-02-13 CN disclosed
EP-2121349-B1 RUBBER COMPOSITION, PROCESS OF PREPARING SAME AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MAT INC (US) 2010-11-17 EP disclosed
CN-101641226-A Rubber composition, method of making the same, and articles made therefrom MOMENTIVE PERFORMANCE MAT INC 2010-02-03 CN disclosed
US-7625965-B2 Rubber composition, process of preparing same and articles made therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-12-01 US disclosed
EP-2121349-A1 RUBBER COMPOSITION, PROCESS OF PREPARING SAME AND ARTICLES MADE THEREFROM Momentive Performance Materials Inc. (US) 2009-11-25 EP disclosed
WO-2008097587-A1 RUBBER COMPOSITION, PROCESS OF PREPARING SAME AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC (US) 2008-08-14 WO disclosed
US-20080194746-A1 Rubber composition, process of preparing same and articles made therefrom MOMENTIVE PERFORMANCE MATERIALS INC. 2008-08-14 US disclosed