SCHEMBL574403

SCHEMBL574403

CCO[Si](OCC)(OCC)C(C)c1ccc(C(C)[Si](OCC)(OCC)OCC)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.33
ALOX15 P16050 2/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
PGR P06401 1/20 0.33
CHRM2 P08172 1/20 0.33
CYP3A4 P08684 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
AR P10275 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPT P10636 1/20 0.33
CHRM1 P11229 1/20 0.33
CYP2C9 P11712 1/20 0.33
DRD1 P21728 1/20 0.33
TBXA2R P21731 1/20 0.33
PTGS1 P23219 1/20 0.33
SLC6A2 P23975 1/20 0.33
CYP2C19 P33261 1/20 0.33
ADRA1A P35348 1/20 0.33
OPRM1 P35372 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27135638 0.94 PTGS2 (0.36) ESR1ALOX15LMNACYP1A2PGR
SCHEMBL28418566 0.92 ESR1 (0.47) ESR1ALOX15LMNACYP1A2PGR
SCHEMBL3397079 0.92 CHRNA7 (0.34) LMNASLC6A3TDP1ALDH1A1
SCHEMBL926681 0.90 TSHR (0.33) TDP1
SCHEMBL929186 0.90 TSHR (0.31) TDP1
SCHEMBL927589 0.90 LMNA (0.32) ESR1ALOX15LMNACYP1A2PGR
SCHEMBL27849347 0.90 CYP1A2 (0.32) CYP1A2CYP2D6
SCHEMBL928450 0.90
SCHEMBL27849330 0.90 GAA (0.36) CYP1A2CHRM2CYP3A4CYP2D6CHRM1
SCHEMBL574617 0.89 TAAR1 (0.39) LMNACYP1A2CYP3A4MAPTCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190015815-A1 SUPERFICIALLY POROUS MATERIALS COMPRISING A COATED CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS WATERS TECHNOLOGIES CORPORATION 2019-01-17 US claimed
EP-3426388-A1 SUPERFICIALLY POROUS MATERIALS COMPRISING A COATED CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS Waters Technologies Corporation (US) 2019-01-16 EP claimed
CN-107075304-A High gain durable anti-reflective coating 恩基科技股份有限公司 2017-08-18 CN claimed
EP-3172260-A2 HIGH GAIN DURABLE ANTI-REFLECTIVE COATING Enki Technology Inc. (US) 2017-05-31 EP claimed
US-9399720-B2 High gain durable anti-reflective coating Enki Technology, Inc. (US) 2016-07-26 US claimed
US-20160032147-A1 HIGH GAIN DURABLE ANTI-REFLECTIVE COATING JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2016-02-04 US claimed
WO-2016011071-A2 HIGH GAIN DURABLE ANTI-REFLECTIVE COATING Enki Technology, Inc. (US) 2016-01-21 WO claimed
EP-2598440-A2 SUPERFICIALLY POROUS MATERIALS COMPRISING A SUBSTANTIALLY NONPOROUS HYBRID CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS Waters Technologies Corporation (US) 2013-06-05 EP claimed
EP-2598441-A1 SUPERFICIALLY POROUS MATERIALS COMPRISING A SUBSTANTIALLY NONPOROUS CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS Waters Technologies Corporation (US) 2013-06-05 EP claimed
WO-2012018598-A1 SUPERFICIALLY POROUS MATERIALS COMPRISING A SUBSTANTIALLY NONPOROUS CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS WATERS TECHNOLOGIES CORPORATION (US) 2012-02-09 WO claimed
WO-2012018596-A2 SUPERFICIALLY POROUS MATERIALS COMPRISING A SUBSTANTIALLY NONPOROUS HYBRID CORE HAVING NARROW PARTICLE SIZE DISTRIBUTION; PROCESS FOR THE PREPARATION THEREOF; AND USE THEREOF FOR CHROMATOGRAPHIC SEPARATIONS WATERS TECHNOLOGIES CORPORATION (US) 2012-02-09 WO claimed
EP-2054344-B1 ORGANIC-INORGANIC HYBRID SILICATES AND METAL-SILICATES HAVING AN ORDERED STRUCTURE ENI SPA (IT) 2011-03-16 EP claimed
EP-1995214-A2 Multifunctional periodic mesoporous organosilica materials using block copolymer template and preparation method thereof Sungkyunkwan University Foundation for Corporate Collaboration (KR) 2008-11-26 EP claimed
US-12623205-B2 Superficially porous materials comprising a substantially nonporous hybrid core having narrow particle size distribution WATERS TECHNOLOGIES CORPORATION (US) 2026-05-12 US disclosed
US-12611617-B2 Chromatographic columns and separation devices comprising a superficially porous material; and use thereof for supercritical fluid chromatography and other chromatography WATERS TECHNOLOGIES CORPORATION (US) 2026-04-28 US disclosed
EP-3834927-B1 METHOD FOR PREPARING A SUPERFICIALLY POROUS MATERIAL WATERS TECHNOLOGIES CORP (US) 2026-03-25 EP disclosed
EP-2131432-A1 ELECTRODE BINDER, ELECTRODE, MEMBRANE-ELECTRODE ASSEMBLY, AND SOLID POLYMER FUEL CELL Sekisui Chemical Co., Ltd. (JP) 2009-12-09 EP disclosed
EP-2128920-A1 PROTON CONDUCTIVE FILM, MEMBRANE-ELECTRODE ASSEMBLY, AND SOLID POLYMER ELECTROLYTE FUEL CELL Sekisui Chemical Co., Ltd. (JP) 2009-12-02 EP disclosed
EP-1995214-A2 Multifunctional periodic mesoporous organosilica materials using block copolymer template and preparation method thereof Sungkyunkwan University Foundation for Corporate Collaboration (KR) 2008-11-26 EP disclosed
US-6020408-A BLEND OF ACRYLIC POLYMER AND ORGANOSILICON COMPOUND LINTEC CORPORATION (JP) 2000-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12611617-B2 Chromatographic columns and separation devices comprising a superficially porous material; and use thereof for supercritical fluid chromatography and other chromatography F11, F12, F2 ESR1 2707/4885ALOX15 3546/4885LMNA 362/4885
US-12623205-B2 Superficially porous materials comprising a substantially nonporous hybrid core having narrow particle size distribution ZYX, FGB, F11 ESR1 1759/4885ALOX15 1936/4885LMNA 172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.