Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | CCNC | P24863 | 1/20 | 0.30 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL314932 | 1.00 | AAK1 (0.33) | AAK1CYP3A4ROCK1CYP4F2CYP4A11 | |
| SCHEMBL314456 | 0.89 | ROCK2 (0.36) | AAK1CYP3A4ROCK1CYP4F2CYP4A11 | |
| SCHEMBL3395493 | 0.89 | ROCK2 (0.36) | AAK1CYP3A4ROCK1CYP4F2CYP4A11 | |
| SCHEMBL315023 | 0.87 | NAAA (0.33) | CYP4F2CYP4A11 | |
| SCHEMBL3398167 | 0.87 | NAAA (0.33) | CYP4F2CYP4A11 | |
| SCHEMBL315134 | 0.87 | CHRNA7 (0.33) | CYP4F2CYP4A11ROCK2 | |
| SCHEMBL315133 | 0.87 | CHRNA7 (0.33) | CYP4F2CYP4A11ROCK2 | |
| SCHEMBL3395501 | 0.85 | PTGES (0.31) | CYP4F2CYP4A11 | |
| SCHEMBL314799 | 0.85 | PTGES (0.31) | CYP4F2CYP4A11 | |
| SCHEMBL3400544 | 0.85 | PIK3C3 (0.33) | CYP3A4ROCK1GSK3BCCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066683-B1 | DERIVATIVES OF 5-THIOXYLOPYRANOSE AND USE OF SAME FOR TREATMENT | FOURNIER LAB SA (FR) | 2010-11-03 | — | — | EP | disclosed |