SCHEMBL339753

SCHEMBL339753

C=C(C)C(=O)NCc1ccc(O)c(O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERCC1 P07992 14/20 0.59
ERCC4 Q92889 14/20 0.59
KDM4E B2RXH2 1/20 0.57
ALDH1A1 P00352 1/20 0.57
LMNA P02545 1/20 0.57
MAPT P10636 1/20 0.57
HPGD P15428 1/20 0.57
PTGS1 P23219 1/20 0.57
BLM P54132 1/20 0.57
HIF1A Q16665 1/20 0.57
HSD17B10 Q99714 1/20 0.57
TRPV1 Q8NER1 1/20 0.52
ALPG P10696 1/20 0.51
ALPL P05186 1/20 0.50
GABRP O00591 1/20 0.49
GABRD O14764 1/20 0.49
GABRA1 P14867 1/20 0.49
GABRB1 P18505 1/20 0.49
GABRG2 P18507 1/20 0.49
GABRB3 P28472 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9187028 0.87 ESR1 (0.49) ERCC1ERCC4KDM4EALDH1A1LMNA
SCHEMBL107288 0.86 ERCC1 (0.66) ERCC1ERCC4TRPV1ALPGALPL
SCHEMBL30446328 0.85 MAPT (0.73) ERCC1ERCC4KDM4EALDH1A1LMNA
SCHEMBL400288 0.85 MAPT (0.73) ERCC1ERCC4KDM4EALDH1A1LMNA
SCHEMBL28232328 0.85 ERCC1 (0.59) ERCC1ERCC4KDM4ELMNAMAPT
SCHEMBL731190 0.84 KMT2A (0.50) ALDH1A1MAPT
SCHEMBL8377488 0.83 MTNR1A (0.59) ALDH1A1HPGDBLMTRPV1GABRP
SCHEMBL5534319 0.83 ERCC1 (0.42) ERCC1ERCC4KDM4EALDH1A1LMNA
SCHEMBL20239098 0.83 SELL (0.43) ERCC1ERCC4KDM4EALDH1A1LMNA
SCHEMBL8269527 0.82 KDM4E (0.69) ERCC1ERCC4KDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110801741-A Surface modification method of polyvinylidene fluoride membrane 济南大学 2020-02-18 CN claimed
US-20230140810-A1 MATERIAL FOR FORMING ADHESIVE FILM, PATTERNING PROCESS, AND METHOD FOR FORMING ADHESIVE FILM SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-04 US disclosed
US-20230140810-A1 MATERIAL FOR FORMING ADHESIVE FILM, PATTERNING PROCESS, AND METHOD FOR FORMING ADHESIVE FILM SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-04 US disclosed
CN-110801741-A Surface modification method of polyvinylidene fluoride membrane 济南大学 2020-02-18 CN disclosed
US-8367091-B2 Coatings for implantable medical devices ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2013-02-05 US disclosed
US-8367091-B2 Coatings for implantable medical devices ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2013-02-05 US disclosed
US-8367091-B2 Coatings for implantable medical devices ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2013-02-05 US disclosed
US-8097268-B2 Coatings for implantable medical devices ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2012-01-17 US disclosed
US-8097268-B2 Coatings for implantable medical devices ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2012-01-17 US disclosed
US-8097268-B2 Coatings for implantable medical devices ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2012-01-17 US disclosed
US-20090252780-A1 COATINGS FOR IMPLANTABLE MEDICAL DEVICES ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2009-10-08 US disclosed
US-20090252780-A1 COATINGS FOR IMPLANTABLE MEDICAL DEVICES ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2009-10-08 US disclosed
US-20090252780-A1 COATINGS FOR IMPLANTABLE MEDICAL DEVICES ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2009-10-08 US disclosed
US-20090248146-A1 COATINGS FOR IMPLANTABLE MEDICAL DEVICES ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2009-10-01 US disclosed
US-20090248146-A1 COATINGS FOR IMPLANTABLE MEDICAL DEVICES ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2009-10-01 US disclosed
US-20090248146-A1 COATINGS FOR IMPLANTABLE MEDICAL DEVICES ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2009-10-01 US disclosed
US-7563454-B1 Coatings for implantable medical devices ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2009-07-21 US disclosed
US-7563454-B1 Coatings for implantable medical devices ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2009-07-21 US disclosed
US-7563454-B1 Coatings for implantable medical devices ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2009-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090252780-A1 COATINGS FOR IMPLANTABLE MEDICAL DEVICES AOC1, TFRC, CD59 ERCC1 1050/4885ERCC4 1841/4885KDM4E 1741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.