SCHEMBL8377488

SCHEMBL8377488

C=C(C)C(=O)NCc1ccc(O)c(OC)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 1/20 0.59
MTNR1B P49286 1/20 0.59
TRPV1 Q8NER1 5/20 0.58
ALDH1A1 P00352 1/20 0.57
CYP1A2 P05177 1/20 0.57
CYP3A4 P08684 1/20 0.57
CYP2D6 P10635 1/20 0.57
CYP2C9 P11712 1/20 0.57
HPGD P15428 1/20 0.57
ALOX15 P16050 1/20 0.57
CYP2C19 P33261 1/20 0.57
BLM P54132 1/20 0.57
PMP22 Q01453 1/20 0.57
ALOX5 P09917 1/20 0.57
OR51E2 Q9H255 1/20 0.57
GABRP O00591 1/20 0.56
GABRD O14764 1/20 0.56
GABRA1 P14867 1/20 0.56
GABRB1 P18505 1/20 0.56
GABRG2 P18507 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28190220 0.88 ALDH1A1 (0.69) ALDH1A1
SCHEMBL19366780 0.87 MTNR1A (0.65) MTNR1AMTNR1BALDH1A1ALOX5OR51E2
SCHEMBL17266370 0.85 ALDH1A1 (0.53) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL5707095 0.85 MTNR1A (0.69) MTNR1AMTNR1BTRPV1ALDH1A1CYP1A2
SCHEMBL28464370 0.84 ALDH1A1 (0.59) TRPV1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL27591942 0.84 ALDH1A1 (0.61) TRPV1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL339753 0.83 ERCC1 (0.59) TRPV1ALDH1A1HPGDBLMGABRP
SCHEMBL297477 0.82 ALDH1A1 (0.64) TRPV1ALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL20239120 0.81 TSHR (0.54) ALDH1A1
SCHEMBL4208734 0.81 ALDH1A1 (0.62) TRPV1ALDH1A1CYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107513123-A One kind is based on catechol structure functionalization silicone-contained acrylic resin solution and its preparation method and application 浙江海洋大学 2017-12-26 CN disclosed
US-20170266353-A1 BIOADHESIVE COMPOUNDS AND METHODS OF SYNTHESIS AND USE DSM IP ASSETS BV (NL) 2017-09-21 US disclosed
CN-102127185-B Acrylic resin with epoxy cycle on side chain and preparation and use thereof UNIV ZHEJIANG OCEAN 2013-01-09 CN disclosed
CN-102127185-A Acrylic resin with epoxy cycle on side chain and preparation and use thereof UNIV ZHEJIANG OCEAN 2011-07-20 CN disclosed
US-5863701-A POLYMERS FOR PHOTORESISTS USED FOR PRINTING PLATES AND CIRCUIT BOARDS OLIN MICROELECTRONIC CHEMICALS, INC. (US) 1999-01-26 US disclosed
US-5780566-A Polymers containing protected styrene and unprotected hydroxybenzyl (meth)acrylamides OLIN MICROELECTRONIC CHEMICALS, INC. (US) 1998-07-14 US disclosed
EP-0709410-A2 Polymers OCG Microelectronic Materials, Inc. (US) 1996-05-01 EP disclosed