Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | CNR2 | P34972 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | GSK3B | P49841 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14006013 | 0.87 | HTT (0.75) | LMNAALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL540958 | 0.85 | TNF (0.73) | LMNAALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL3431636 | 0.82 | ALDH1A1 (0.79) | LMNAALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL28943970 | 0.80 | KDM4E (0.73) | LMNAALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL29737404 | 0.80 | KDM4E (0.73) | LMNAALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL6446137 | 0.79 | LMNA (0.69) | LMNAALDH1A1HTTSMN1; SMN2TSHR | |
| SCHEMBL6809570 | 0.79 | MEN1 (0.53) | LMNAKDM4EHTTL3MBTL1TP53 | |
| SCHEMBL20715463 | 0.78 | RAB9A (0.76) | LMNAKDM4ESMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL5009001 | 0.77 | HPGD (0.70) | LMNAALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL20762588 | 0.76 | KDM4E (0.51) | LMNAALDH1A1KDM4EHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100297038-A1 | Benzimidazole Derivatives And Their Use As Cooling Agents | GIVAUDAN S.A. (CH) | 2010-11-25 | — | — | US | claimed |
| EP-2250154-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS COOLING AGENTS | Givaudan SA (CH) | 2010-11-17 | — | — | EP | claimed |
| WO-2009089641-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS COOLING AGENTS | GIVAUDAN SA (CH) | 2009-07-23 | — | — | WO | claimed |
| US-20100297038-A1 | Benzimidazole Derivatives And Their Use As Cooling Agents | GIVAUDAN S.A. (CH) | 2010-11-25 | — | — | US | disclosed |
| EP-2250154-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS COOLING AGENTS | Givaudan SA (CH) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009089641-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS COOLING AGENTS | GIVAUDAN SA (CH) | 2009-07-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100297038-A1 | Benzimidazole Derivatives And Their Use As Cooling Agents | OR10J3, H1-3, ORC3 | LMNA 1041/4885ALDH1A1 640/4885KDM4E 1636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.