Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KIF11 | P52732 | 1/20 | 0.53 |
| ▸ | GUSB | P08236 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3398149 | 0.85 | KIF11 (0.71) | USP2HTTKIF11GUSBPKM | |
| SCHEMBL13789190 | 0.84 | USP2 (0.79) | USP2HSD17B10ALDH1A1TDP1 | |
| SCHEMBL19732923 | 0.84 | USP2 (0.79) | USP2HSD17B10ALDH1A1TDP1 | |
| SCHEMBL19732955 | 0.84 | USP2 (0.79) | USP2HSD17B10ALDH1A1TDP1 | |
| SCHEMBL6348122 | 0.84 | HTT (0.75) | USP2HTTKIF11GUSBPKM | |
| SCHEMBL14413255 | 0.84 | PKM (0.68) | USP2HTTKIF11GUSBPKM | |
| SCHEMBL19732936 | 0.84 | PKM (0.68) | USP2HTTKIF11GUSBPKM | |
| SCHEMBL14413847 | 0.84 | KIF11 (0.77) | KIF11PKMHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL14413854 | 0.82 | NPSR1 (0.69) | USP2HTTKIF11GUSBALDH1A1 | |
| SCHEMBL19732952 | 0.82 | NPSR1 (0.69) | USP2HTTKIF11GUSBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889016-A | Dihydropyrimidone derivatives as NPY antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-30 | — | — | US | disclosed |