Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13072002 | 0.92 | HTR2C (0.46) | HTR2CLMNACES2 | |
| SCHEMBL3397121 | 0.92 | HTR2C (0.46) | HTR2CLMNACES2 | |
| SCHEMBL3405168 | 0.88 | HTR2C (0.46) | HTR2CALDH1A1HPGDSMN1; SMN2SCN10A | |
| SCHEMBL3405561 | 0.85 | ALDH1A1 (0.53) | ALDH1A1HPGDSMN1; SMN2SCN10ALMNA | |
| SCHEMBL3401061 | 0.84 | RORC (0.47) | HTR2CALDH1A1SCN9ARORCSMN1; SMN2 | |
| SCHEMBL3398198 | 0.84 | HTR2C (0.55) | HTR2CALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL3402380 | 0.84 | THRA (0.45) | HTR2CALDH1A1HPGDSMN1; SMN2SCN10A | |
| SCHEMBL3404145 | 0.83 | ALDH1A1 (0.60) | HTR2CALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3402202 | 0.83 | HTR2C (0.44) | HTR2CALDH1A1RORCSMN1; SMN2CES2 | |
| SCHEMBL3398944 | 0.83 | ALDH1A1 (0.45) | HTR2CALDH1A1HPGDSCN9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728009-B1 | Thiazole amides, imidazole amides and related analogues | NEUROGEN CORPORATION (US) | 2010-06-01 | — | — | US | disclosed |
| US-7728009-B1 | Thiazole amides, imidazole amides and related analogues | NEUROGEN CORPORATION (US) | 2010-06-01 | — | — | US | disclosed |
| US-7728009-B1 | Thiazole amides, imidazole amides and related analogues | NEUROGEN CORPORATION (US) | 2010-06-01 | — | — | US | disclosed |
| WO-2006089076-A9 | THIAZOLE AMIDES, IMIDAZOLE AMIDES AND RELATED ANALOGUES | NEUROGEN CORP (US) | 2007-04-26 | — | — | WO | disclosed |