SCHEMBL3399995

SCHEMBL3399995

CC(C)N(C(=O)c1ccc(-c2ccc3[nH]c(=O)ccc3c2)cc1)C(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.46
HPGD P15428 3/20 0.45
NPSR1 Q6W5P4 2/20 0.45
MCOLN3 Q8TDD5 2/20 0.45
CA12 O43570 1/20 0.44
CA9 Q16790 1/20 0.44
F11 P03951 1/20 0.41
MAPT P10636 4/20 0.41
PTGS2 P35354 2/20 0.40
LMNA P02545 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
POLB P06746 2/20 0.39
RXFP1 Q9HBX9 1/20 0.39
THRB P10828 1/20 0.39
PIK3CD O00329 1/20 0.39
ABL1 P00519 1/20 0.39
EGFR P00533 1/20 0.39
HCK P08631 1/20 0.39
SRC P12931 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10368097 0.77 CA12 (0.47) RIPK1HPGDCA12CA9F11
SCHEMBL10366373 0.77 GRIK1 (0.58) HPGDCA12CA9F11LMNA
SCHEMBL10366372 0.76 CA12 (0.46) HPGDCA12CA9F11MAPT
SCHEMBL4290533 0.74 CA12 (0.53) CA12CA9F11AR
SCHEMBL16573987 0.74 CA12 (0.73) HPGDCA12CA9F11MAPT
SCHEMBL4553772 0.73 MAPT (0.53) CA12CA9F11MAPTLMNA
SCHEMBL29374162 0.73 BRPF1 (0.45) RIPK1HPGDNPSR1MCOLN3CA12
SCHEMBL4552802 0.72 CA12 (0.57) HPGDCA12CA9F11POLB
SCHEMBL4553299 0.72 MAPT (0.52) CA12CA9F11MAPTLMNA
SCHEMBL18713523 0.71 CA12 (0.47) CA12CA9F11MAPTPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122060893-A KASP molecular marker associated with erigeron breviscapus ester B and application thereof 云南农业大学 2026-05-19 CN disclosed
EP-4720072-A2 RAS INHIBITORS Revolution Medicines, Inc. (US) 2026-04-08 EP disclosed
US-20260078133-A1 RAS INHIBITORS Revolution Medicines, Inc. 2026-03-19 US disclosed
US-12576109-B2 Allogeneic human plasma and platelet derived products and uses thereof CONSANO BIO, INC. (US) 2026-03-17 US disclosed
US-20250302873-A1 ALLOGENEIC HUMAN PLASMA AND PLATELET DERIVED PRODUCTS AND USES THEREOF CONSANO BIO, INC. 2025-10-02 US disclosed
WO-2024249299-A2 RAS INHIBITORS Revolution Medicines, Inc. (US) 2024-12-05 WO disclosed
US-20230313189-A1 COMPLEMENT COMPONENT 4 INHIBITORS FOR TREATING NEUROLOGICAL DISEASES, AND RELATED COMPOSITONS, SYSTEMS AND METHODS OF USING SAME GENENTECH, INC. (US) 2023-10-05 US disclosed
CN-112736923-B Natural gas network cascading failure assessment control method considering power grid failure influence 华南理工大学 2023-06-20 CN disclosed
US-20230056230-A1 Therapy for the Treatment of Cancer MACROGENICS, INC. (US) 2023-02-23 US disclosed
EP-4081248-A1 THERAPY FOR THE TREATMENT OF CANCER MacroGenics, Inc. (US) 2022-11-02 EP disclosed
CN-114901306-A Therapy for the treatment of cancer 宏观基因有限公司 2022-08-12 CN disclosed
EP-2126053-B1 APOCRINE CELL LINE UNILEVER PLC (GB) 2010-11-17 EP disclosed
US-20100184213-A1 APOCRINE CELL LINE CONOPCO, INC. D/B/A UNILEVER 2010-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078133-A1 RAS INHIBITORS KRAS, NRAS, HRAS RIPK1 2325/4885HPGD 4265/4885NPSR1 3975/4885
US-12576109-B2 Allogeneic human plasma and platelet derived products and uses thereof FGB, PDGFRB, PDGFA RIPK1 3979/4885HPGD 2789/4885NPSR1 3533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.