Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.51 |
| ▸ | ESRRG | P62508 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3400227 | 0.99 | EPHX2 (0.50) | EPHX2NR1H4ESRRGHDAC1POLB | |
| SCHEMBL907337 | 0.89 | EPHX2 (0.51) | EPHX2NR1H4ESRRGHDAC1POLB | |
| Hydrochloric Acid SCHEMBL3724825 | 0.85 | MAOB (0.43) | LMNARAB9A | |
| SCHEMBL7947659 | 0.85 | KIF11 (0.49) | EPHX2NR1H4ESRRGALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL3714477 | 0.84 | ALDH1A1 (0.42) | HDAC1ALDH1A1LMNAMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL3718123 | 0.84 | HDAC6 (0.45) | ESRRGHDAC1POLBALDH1A1LMNA | |
| SCHEMBL907583 | 0.83 | NR1H4 (0.54) | EPHX2NR1H4ESRRGALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL3717428 | 0.82 | OGG1 (0.44) | HDAC1POLBALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL3714962 | 0.82 | ALDH1A1 (0.44) | POLBALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL6816272 | 0.82 | EPHX2 (0.67) | EPHX2NR1H4LMNAMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8501991-B2 | P53 activating compounds | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2013-08-06 | — | — | US | disclosed |
| EP-2099445-B1 | P53 ACTIVATING BENZOYL UREA AND BENZOYL THIOUREA COMPOUNDS | UNIV DUNDEE (GB) | 2010-11-17 | — | — | EP | disclosed |
| EP-2099445-A2 | P53 ACTIVATING BENZOYL UREA AND BENZOYL THIOUREA COMPOUNDS | University Court of The University of Dundee (GB) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008029096-A2 | P53 ACTIVATING BENZOYL UREA AND BENZOYL THIOUREA COMPOUNDS | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2008-03-13 | — | — | WO | disclosed |