SCHEMBL340066

SCHEMBL340066

Cc1ccc(-c2ccc(C)cc2O)c(O)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.68
TP53 P04637 3/20 0.57
TDP1 Q9NUW8 1/20 0.57
LMNA P02545 2/20 0.54
CHRM1 P11229 1/20 0.54
SLC6A2 P23975 1/20 0.54
ADRA1A P35348 1/20 0.54
HTR2B P41595 1/20 0.54
ALOX15 P16050 3/20 0.52
HSD17B10 Q99714 3/20 0.52
ALDH1A1 P00352 2/20 0.52
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
ACHE P22303 3/20 0.50
MAPT P10636 2/20 0.50
HPGD P15428 2/20 0.50
ALOX12 P18054 2/20 0.50
GAA P10253 1/20 0.50
SELL P14151 1/20 0.50
SELP P16109 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29819939 1.00 TRPA1 (0.68) TRPA1TP53TDP1LMNACHRM1
SCHEMBL26437159 0.89 TRPA1 (0.56) TRPA1TP53TDP1LMNACHRM1
SCHEMBL18826204 0.85 SELL (0.56) TRPA1TP53TDP1LMNACHRM1
SCHEMBL12342210 0.85 TRPA1 (0.52) TRPA1TP53TDP1LMNACHRM1
SCHEMBL14293295 0.85 ALDH1A1 (0.64) TRPA1TP53TDP1LMNACHRM1
SCHEMBL31546169 0.84 TRPA1 (0.56) TRPA1TP53TDP1LMNACHRM1
SCHEMBL10068940 0.84 TRPA1 (0.56) TRPA1TP53TDP1LMNACHRM1
SCHEMBL17753387 0.83 TRPA1 (0.56) TRPA1TP53TDP1LMNACHRM1
SCHEMBL25878367 0.83 TRPA1 (0.50) TRPA1TP53TDP1LMNACHRM1
SCHEMBL10194996 0.82 TRPA1 (0.54) TRPA1TP53TDP1LMNACHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0509740-B1 Heat-developable photosensitive material and image forming method making use of the heat-developable photosensitive material CANON KK (JP) 1996-06-26 EP claimed
EP-3307840-B1 FOOD OR BEVERAGE PACKAGES AND METHODS OF COATING SUCH PACKAGES PPG IND OHIO INC (US) 2020-08-05 EP disclosed
US-20200031995-A1 Food or Beverage Packages and Methods of Coating Such Packages PPG INDUSTRIES OHIO, INC. (US) 2020-01-30 US disclosed
US-9315435-B2 Method for producing hydroxyphenylcyclohexanol compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-04-19 US disclosed
US-20150141707-A1 METHOD FOR PRODUCING HYDROXYPHENYLCYCLOHEXANOL COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-05-21 US disclosed
EP-2842930-A1 METHOD FOR PRODUCING HYDROXYPHENYLCYCLOHEXANOL COMPOUND Sumitomo Chemical Company Limited (JP) 2015-03-04 EP disclosed
EP-2271651-B1 ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS DOW GLOBAL TECHNOLOGIES LLC (US) 2014-01-01 EP disclosed
EP-2346887-B1 SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES DOW TECHNOLOGY INVESTMENTS LLC (US) 2013-12-25 EP disclosed
US-8546600-B2 Slurry process for synthesis of bisphosphites and situ use thereof for producing bisphosphite DOW TECHNOLOGY INVESTMENTS LLC 2013-10-01 US disclosed
EP-2257560-B1 SLURRY PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS UNION CARBIDE CHEM PLASTIC (US) 2013-07-17 EP disclosed
EP-2271651-A1 ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS Dow Global Technologies Inc. (US) 2011-01-12 EP disclosed
EP-2257560-A1 SLURRY PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS Union Carbide Chemicals & Plastics Technology Llc (Formerly Union Carbide Chemicals & Plastics Technology Corporation) (US) 2010-12-08 EP disclosed
WO-2010042313-A1 SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES DOW TECHNOLOGY INVESTMENTS LLC (US) 2010-04-15 WO disclosed
WO-2009120529-A1 SLURRY PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC (FORMERLY UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION) (US) 2009-10-01 WO disclosed
WO-2009120210-A1 ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS DOW GLOBAL TECHNOLOGIES INC. (US) 2009-10-01 WO disclosed
US-20090247790-A1 ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS UNION CARBIDE CORPORATION 2009-10-01 US disclosed
US-20090045725-A1 POLYARYLENE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-02-19 US disclosed
EP-0509740-B1 Heat-developable photosensitive material and image forming method making use of the heat-developable photosensitive material CANON KK (JP) 1996-06-26 EP disclosed
US-5262295-A Biphenyldihydroxide reducing agent for silver halide emulsion layers CANON KABUSHIKI KAISHA (JP) 1993-11-16 US disclosed
EP-0509740-A1 Heat-developable photosensitive material and image forming method making use of the heat-developable photosensitive material CANON KABUSHIKI KAISHA (JP) 1992-10-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150141707-A1 METHOD FOR PRODUCING HYDROXYPHENYLCYCLOHEXANOL COMPOUND HSD11B2, CYP21A2, CYP11B2 TRPA1 2672/4885TP53 1836/4885TDP1 4423/4885
US-20090247790-A1 ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS PIM3, PLCB3, PLCD1 TRPA1 1954/4885TP53 4527/4885TDP1 4022/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.