Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3400065 | 0.91 | L3MBTL3 (0.48) | LMNAALDH1A1L3MBTL1KDM4EL3MBTL3 | |
| SCHEMBL3404126 | 0.91 | L3MBTL3 (0.48) | LMNAALDH1A1L3MBTL1KDM4EL3MBTL3 | |
| SCHEMBL3405473 | 0.86 | KDM4E (0.47) | LMNAALDH1A1L3MBTL1KDM4EHPGD | |
| SCHEMBL3403915 | 0.82 | KMT2A (0.48) | LMNAALDH1A1L3MBTL1KDM4EHPGD | |
| SCHEMBL3400858 | 0.82 | LMNA (0.51) | LMNAALDH1A1OPRM1PDE4BPDE4D | |
| SCHEMBL2201414 | 0.79 | L3MBTL3 (0.42) | LMNAALDH1A1L3MBTL1KDM4EL3MBTL3 | |
| SCHEMBL3398423 | 0.79 | KMT2A (0.60) | LMNAALDH1A1KDM4EHPGDPDE4D | |
| SCHEMBL2200600 | 0.78 | KMT2A (0.46) | LMNAALDH1A1L3MBTL1KDM4ESCN5A | |
| SCHEMBL2200597 | 0.78 | KMT2A (0.46) | LMNAALDH1A1L3MBTL1KDM4ESCN5A | |
| SCHEMBL2202742 | 0.77 | KMT2A (0.50) | ALDH1A1L3MBTL1KDM4EL3MBTL3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728009-B1 | Thiazole amides, imidazole amides and related analogues | NEUROGEN CORPORATION (US) | 2010-06-01 | — | — | US | disclosed |