⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21870597 | 1.00 | — | — | |
| SCHEMBL20093337 | 0.93 | — | — | |
| SCHEMBL2118584 | 0.93 | — | — | |
| Trimethylammonium SCHEMBL27467322 | 0.87 | ALDH1A1 (0.33) | — | |
| SCHEMBL10866756 | 0.84 | — | — | |
| Bicarbonate SCHEMBL28006850 | 0.83 | ALDH1A1 (0.38) | — | |
| SCHEMBL28109704 | 0.81 | — | — | |
| SCHEMBL3840016 | 0.76 | GNAI3 (0.47) | — | |
| SCHEMBL29348153 | 0.75 | ALDH1A1 (0.34) | — | |
| SCHEMBL11654259 | 0.75 | LMNA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110756002-A | Absorption liquid and method for recovering sulfur from gas containing hydrogen sulfide and sulfur dioxide | 中国石油化工股份有限公司 | 2020-02-07 | — | — | CN | claimed |
| EP-3150593-B1 | SMALL MOLECULE MYRISTATE INHIBITORS OF BCR-ABL AND METHODS OF USE | DANA FARBER CANCER INST INC (US) | 2019-04-24 | — | — | EP | claimed |
| EP-3150593-A1 | SMALL MOLECULE MYRISTATE INHIBITORS OF BCR-ABL AND METHODS OF USE | Dana Farber Cancer Institute, Inc. (US) | 2017-04-05 | — | — | EP | claimed |
| US-8921336-B2 | Small molecule myristate inhibitors of BCR-ABL and methods of use | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2014-12-30 | — | — | US | claimed |
| US-20110312908-A1 | SMALL MOLECULE MYRISTATE INHIBITORS OF BCR-ABL AND METHODS OF USE | THE SCRIPPS RESEARCH INSTITUTE | 2011-12-22 | — | — | US | claimed |
| US-20240158403-A1 | SMALL MOLECULE MYRISTATE INHIBITORS OF BCR-ABL AND METHODS OF USE | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-05-16 | — | — | US | disclosed |
| US-11932646-B2 | Small molecule myristate inhibitors of Bcr-abl and methods of use | THE SCRIPPS RESEARCH INSTITUTE (US) | 2024-03-19 | — | — | US | disclosed |
| US-20230348359-A1 | IONIZABLE LIPIDS FOR NANOMATERIALS | BEAM THERAPEUTICS INC. (US) | 2023-11-02 | — | — | US | disclosed |
| US-20220135573-A1 | SMALL MOLECULE MYRISTATE INHIBITORS OF BCR-ABL AND METHODS OF USE | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-05-05 | — | — | US | disclosed |
| US-11254682-B2 | Small molecule myristate inhibitors of Bcr-abl and methods of use | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-02-22 | — | — | US | disclosed |
| EP-3912973-A2 | SMALL MOLECULE MYRISTATE INHIBITORS OF BCR-ABL AND METHODS OF USE | Dana-Farber Cancer Institute, Inc. (US) | 2021-11-24 | — | — | EP | disclosed |
| US-20200347068-A1 | SMALL MOLECULE MYRISTATE INHIBITORS OF BCR-ABL AND METHODS OF USE | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-11-05 | — | — | US | disclosed |
| US-20110312908-A1 | SMALL MOLECULE MYRISTATE INHIBITORS OF BCR-ABL AND METHODS OF USE | THE SCRIPPS RESEARCH INSTITUTE | 2011-12-22 | — | — | US | disclosed |
| CN-101888780-A | Quinolone analogs and methods related thereto | CYLENE PHARMACEUTICALS INC | 2010-11-17 | — | — | CN | disclosed |
| EP-2222162-A2 | SMALL MOLECULE MYRISTATE INHIBITORS OF BCR-ABL AND METHODS OF USE | Dana Farber Cancer Institute (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009073153-A2 | SMALL MOLECULE MYRISTATE INHIBITORS OF BCR-ABL AND METHODS OF USE | DANA FARBER CANCER INSTITUTE (US) | 2009-06-11 | — | — | WO | disclosed |
| US-20090068116-A1 | Chemical system with self-timing indicator | INFECTION PREVENTION SYSTEM, INC. (US) | 2009-03-12 | — | — | US | disclosed |
| CN-101137437-A | Basic ionic liquids | UNIV BELFAST (GB) | 2008-03-05 | — | — | CN | disclosed |
| US-4192883-A | ANTITUSSIVES | PIERRE FABRE, S.A. (FR) | 1980-03-11 | — | — | US | disclosed |
| US-4122199-A | Amides of pyrrolidinoethylamine which can be used in treatment of coughs | PIERRE FABRE S.A. (FR) | 1978-10-24 | — | — | US | disclosed |