Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 3/20 | 0.47 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 4/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10942762 | 0.98 | GNAI3 (0.50) | GNAI3GNAO1GNAI1S1PR1S1PR3 | |
| SCHEMBL26708656 | 0.92 | GNAI3 (0.44) | GNAI3GNAO1GNAI1S1PR1S1PR3 | |
| SCHEMBL7750084 | 0.91 | GNAI3 (0.47) | GNAI3GNAO1GNAI1S1PR1S1PR3 | |
| SCHEMBL27552046 | 0.88 | S1PR1 (0.41) | GNAI3GNAO1GNAI1S1PR1S1PR3 | |
| SCHEMBL17517004 | 0.86 | S1PR1 (0.40) | GNAI3GNAO1GNAI1S1PR1S1PR3 | |
| SCHEMBL28109704 | 0.85 | — | — | |
| Dimethylamine SCHEMBL7245572 | 0.83 | S1PR1 (0.41) | GNAI3GNAO1GNAI1S1PR1S1PR3 | |
| SCHEMBL2902792 | 0.79 | KEAP1 (0.34) | — | |
| SCHEMBL11654259 | 0.79 | LMNA (0.38) | GNAI3GNAO1GNAI1S1PR1S1PR3 | |
| SCHEMBL23767407 | 0.79 | S1PR1 (0.49) | GNAI3GNAO1GNAI1S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087991-B1 | PRODRUGS OF DIPEPTIDYL PEPTIDASE IV INHIBITORS | PROSIDION LTD (GB) | 2009-09-02 | — | — | EP | claimed |
| CN-105263927-B | Inhibitors of glutaminyl cyclase | 前体生物药物股份公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-108218849-A | New inhibitor | 前体生物药物股份公司 | 2018-06-29 | — | — | CN | disclosed |
| CN-1196483-C | Compositions for improivng fertility | FERRING BV (NL) | 2005-04-13 | — | — | CN | disclosed |
| WO-2004076433-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | AIC (BE) | 2004-09-10 | — | — | WO | disclosed |
| WO-2004076434-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | AIC (BE) | 2004-09-10 | — | — | WO | disclosed |
| CN-1359293-A | Pharmaceutical compositions comprising dipeptidy peptidase in inhibitors for the promotion of growth | FERRING BV (NL) | 2002-07-17 | — | — | CN | disclosed |
| CN-1352557-A | Fertility enhancing composition | FERRING BV (NL) | 2002-06-05 | — | — | CN | disclosed |