SCHEMBL3401384

SCHEMBL3401384

COc1cc(OC)c(-c2ccccn2)c(OC)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 6/20 0.52
SMN1; SMN2 Q16637 6/20 0.52
LMNA P02545 5/20 0.52
ALDH1A1 P00352 4/20 0.52
TDP1 Q9NUW8 2/20 0.52
HSP90AA1 P07900 1/20 0.49
CCR1 P32246 2/20 0.47
CCR5 P51681 2/20 0.47
CCR8 P51685 2/20 0.47
NPC1 O15118 3/20 0.47
RAB9A P51151 2/20 0.47
TRPM8 Q7Z2W7 1/20 0.47
RUNX1 Q01196 1/20 0.47
POLB P06746 3/20 0.46
KDM4E B2RXH2 3/20 0.46
CYP1A2 P05177 1/20 0.46
METAP1 P53582 1/20 0.46
BLM P54132 1/20 0.46
HIF1A Q16665 1/20 0.46
DOHH Q9BU89 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5462166 0.82 SMN1; SMN2 (0.55) L3MBTL1SMN1; SMN2LMNAALDH1A1TDP1
SCHEMBL29496938 0.81 SYK (0.56) L3MBTL1SMN1; SMN2LMNAALDH1A1TDP1
SCHEMBL5379182 0.81 SYK (0.56) L3MBTL1SMN1; SMN2LMNAALDH1A1TDP1
SCHEMBL30525959 0.81 SYK (0.56) L3MBTL1SMN1; SMN2LMNAALDH1A1TDP1
SCHEMBL5328683 0.80 CCR1 (0.50) L3MBTL1SMN1; SMN2LMNAALDH1A1TDP1
SCHEMBL28208710 0.79 CYP1A2 (0.56) L3MBTL1SMN1; SMN2LMNAHSP90AA1CCR1
SCHEMBL8248415 0.79 NPC1 (0.52) L3MBTL1SMN1; SMN2LMNAALDH1A1TDP1
SCHEMBL197885 0.79 HSP90AA1 (0.66) L3MBTL1SMN1; SMN2LMNAALDH1A1TDP1
SCHEMBL29496943 0.77 SYK (0.56) L3MBTL1SMN1; SMN2LMNAALDH1A1TDP1
SCHEMBL31689354 0.77 SMN1; SMN2 (0.50) L3MBTL1SMN1; SMN2LMNAALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8216856-B2 Luminescent lanthanide labelling reagents and their use ABACUS DIAGNOSTICA OY (FI) 2012-07-10 US disclosed
EP-2052252-B1 LUMINESCENT LANTHANIDE LABELLING REAGENTS AND THEIR USE ABACUS DIAGNOSTICA OY (FI) 2010-11-10 EP disclosed
US-20100081211-A1 LUMINESCENT LANTHANIDE LABELLING REAGENTS AND THEIR USE ABACUS DIAGNOSTICA OY (FI) 2010-04-01 US disclosed
EP-2052252-A1 LUMINESCENT LANTHANIDE LABELLING REAGENTS AND THEIR USE Abacus Diagnostica OY (FI) 2009-04-29 EP disclosed
WO-2008020113-A1 LUMINESCENT LANTHANIDE LABELLING REAGENTS AND THEIR USE ABACUS DIAGNOSTICA OY (FI) 2008-02-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100081211-A1 LUMINESCENT LANTHANIDE LABELLING REAGENTS AND THEIR USE SCLY, SRM, TST L3MBTL1 60/4885SMN1; SMN2 3733/4885LMNA 4126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.