Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29354025 | 1.00 | TSHR (0.51) | TSHRALDH1A1L3MBTL1HTTMEN1 | |
| SCHEMBL6114257 | 0.79 | GABRP (0.42) | TSHRALDH1A1L3MBTL1HTTKMT2A | |
| 2-Methyl-D-Diboa SCHEMBL13135829 | 0.79 | ALDH1A1 (0.54) | TSHRALDH1A1L3MBTL1HTTMEN1 | |
| SCHEMBL28045866 | 0.79 | EGFR (0.41) | TSHRALDH1A1L3MBTL1HTTMEN1 | |
| SCHEMBL18128200 | 0.79 | TSHR (0.54) | TSHRALDH1A1L3MBTL1HTTMEN1 | |
| SCHEMBL10130351 | 0.79 | TSHR (0.58) | TSHRALDH1A1MEN1KMT2APDE3B | |
| SCHEMBL10130347 | 0.79 | TSHR (0.58) | TSHRALDH1A1MEN1KMT2APDE3B | |
| SCHEMBL10129864 | 0.79 | TSHR (0.58) | TSHRALDH1A1MEN1KMT2APDE3B | |
| SCHEMBL30036591 | 0.79 | AADAT (0.41) | TSHRALDH1A1L3MBTL1HTTMEN1 | |
| SCHEMBL1562017 | 0.79 | AADAT (0.41) | TSHRALDH1A1L3MBTL1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019200202-A1 | ANTAGONISTS OF HUMAN INTEGRIN (ALPHA4)(BETA7) | MORPHIC THERAPEUTIC, INC. (US) | 2019-10-17 | — | — | WO | disclosed |
| EP-2250169-A1 | PYRIDO [4, 3-D]PYRIMIDINONE DERIVATIVES AS KINASE INHIBITORS | IRM LLC (BM) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009099801-A1 | PYRIDO [4, 3-D] PYRIMIDINONE DERIVATIVES AS KINASE INHIBITORS | IRM LLC (BM) | 2009-08-13 | — | — | WO | disclosed |