Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 8/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29999046 | 0.79 | AADAT (0.42) | ALDH1A1L3MBTL1KMT2AP2RX4TSHR | |
| SCHEMBL914002 | 0.79 | AADAT (0.42) | ALDH1A1L3MBTL1KMT2AP2RX4TSHR | |
| SCHEMBL29354025 | 0.79 | TSHR (0.51) | ALDH1A1L3MBTL1KMT2ATSHRHTT | |
| SCHEMBL3401752 | 0.79 | TSHR (0.51) | ALDH1A1L3MBTL1KMT2ATSHRHTT | |
| SCHEMBL6114257 | 0.78 | GABRP (0.42) | EGFRALDH1A1L3MBTL1KDM4EHPGD | |
| SCHEMBL15957026 | 0.75 | GABRP (0.40) | EGFRALDH1A1L3MBTL1KDM4EHPGD | |
| SCHEMBL14507328 | 0.75 | PPARG (0.42) | ALDH1A1L3MBTL1KDM4EHPGDTSHR | |
| SCHEMBL1562017 | 0.74 | AADAT (0.41) | EGFRALDH1A1L3MBTL1KDM4EHPGD | |
| SCHEMBL19592502 | 0.74 | AADAT (0.41) | EGFRALDH1A1L3MBTL1KDM4EHPGD | |
| Bromide SCHEMBL6851177 | 0.74 | ALDH1A1 (0.38) | EGFRALDH1A1L3MBTL1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105218565-A | Spiral shell oxindole compounds and the purposes as therapeutical agent thereof | XENON PHARMACEUTICALS INC | 2016-01-06 | — | — | CN | disclosed |
| CN-105175433-A | Spiro-oxindole compounds and their use as therapeutic agents | XENON PHARMACEUTICALS INC | 2015-12-23 | — | — | CN | disclosed |