SCHEMBL34021

SCHEMBL34021

CCOc1cccc(C(CC)c2cccc(OCC)c2O)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.47
TYR P14679 1/20 0.47
ACHE P22303 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
GLA P06280 1/20 0.46
ALDH1A1 P00352 2/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C19 P33261 1/20 0.42
KDM4E B2RXH2 2/20 0.41
KMT2A Q03164 2/20 0.41
ALOX15 P16050 2/20 0.40
HPGD P15428 2/20 0.40
IGF1R P08069 1/20 0.40
MAPT P10636 1/20 0.40
BACE1 P56817 1/20 0.40
HSD17B10 Q99714 1/20 0.40
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
CASP3 P42574 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18606582 0.85 L3MBTL1 (0.43) BCHETYRACHEL3MBTL1GLA
SCHEMBL9460657 0.85 ALDH1A1 (0.44) BCHETYRACHEL3MBTL1GLA
SCHEMBL9967744 0.85 GABRA1 (0.59) L3MBTL1GLAALDH1A1CYP2C19KDM4E
SCHEMBL674008 0.83 ALDH1A1 (0.52) L3MBTL1GLAALDH1A1KDM4EKMT2A
SCHEMBL9825698 0.83 ALDH1A1 (0.52) L3MBTL1GLAALDH1A1KDM4EKMT2A
SCHEMBL9206626 0.81 ALDH1A1 (0.44) L3MBTL1GLAALDH1A1CYP2D6KDM4E
SCHEMBL2463787 0.81 L3MBTL1 (0.47) L3MBTL1GLAALDH1A1CYP2C19KDM4E
SCHEMBL2463791 0.81 L3MBTL1 (0.47) L3MBTL1GLAALDH1A1CYP2C19KDM4E
SCHEMBL7208889 0.80 ALDH1A1 (0.43) L3MBTL1GLAALDH1A1KDM4EKMT2A
SCHEMBL1053091 0.79 ALDH1A1 (0.58) BCHETYRACHEL3MBTL1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10088447-A None JP disclosed
US-9345670-B2 Patch preparation NITTO DENKO CORPORATION (JP) 2016-05-24 US disclosed
US-8758312-B2 Patch preparation NITTO DENKO CORPORATION (JP) 2014-06-24 US disclosed
EP-2548551-B1 Patch preparation NITTO DENKO CORP (JP) 2014-05-14 EP disclosed
US-20140066865-A1 PATCH PREPARATION NITTO DENKO CORPORATION (JP) 2014-03-06 US disclosed
EP-2702968-A1 A patch comprising a three layer support NITTO DENKO CORPORATION (JP) 2014-03-05 EP disclosed
US-8506992-B2 Percutaneous absorption-type pharmaceutical preparations NITTO DENKO CORPORATION (JP) 2013-08-13 US disclosed
US-20130023839-A1 PATCH PREPARATION NITTO DENKO CORPORATION (JP) 2013-01-24 US disclosed
EP-2548551-A1 Patch preparation NITTO DENKO CORPORATION (JP) 2013-01-23 EP disclosed
US-20110056609-A1 ADHESIVE PREPARATION NITTO DENKO CORPORATION (JP) 2011-03-10 US disclosed
EP-1925300-B1 Adhesive preparation NITTO DENKO CORP (JP) 2010-11-17 EP disclosed
EP-1759693-B1 Percutaneous absorption-type pharmaceutical preparations NITTO DENKO CORP (JP) 2010-06-23 EP disclosed
EP-1925300-A2 Adhesive preparation NITTO DENKO CORPORATION (JP) 2008-05-28 EP disclosed
US-20080118725-A1 ADHESIVE PREPARATION NITTO DENKO CORPORATION (JP) 2008-05-22 US disclosed
US-20070053967-A1 Percutaneous absorption-type pharmaceutical preparations NITTO DENKO CORPORATION 2007-03-08 US disclosed
EP-1759693-A2 Percutaneous absorption-type pharmaceutical preparations NITTO DENKO CORPORATION (JP) 2007-03-07 EP disclosed
EP-0569862-B1 Medical adhesive sheet and medical preparation NITTO DENKO CORP (JP) 1998-08-12 EP disclosed
JP-H1088447-A WOVEN AND KNITTED GOODS OF SILK LIKE POLYESTER TEIJIN LTD 1998-04-07 JP disclosed
US-5374429-A Pressure sensitive adhesive laminated on polyester nonwoven fabric NITTO DENKO CORPORATION (JP) 1994-12-20 US disclosed
EP-0569862-A2 Medical adhesive sheet and medical preparation NITTO DENKO CORPORATION (JP) 1993-11-18 EP disclosed