SCHEMBL2463791

SCHEMBL2463791

CCOc1cccc([C@@H](O)C(=O)O)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.47
GLA P06280 1/20 0.47
FABP4 P15090 1/20 0.46
FABP5 Q01469 1/20 0.46
PTGS1 P23219 1/20 0.42
PTGS2 P35354 1/20 0.42
MRGPRX4 Q96LA9 1/20 0.41
KLK1 P06870 1/20 0.40
KLK5 Q9Y337 1/20 0.40
TTR P02766 1/20 0.40
CTDSP1 Q9GZU7 1/20 0.40
GAA P10253 2/20 0.40
HCRTR1 O43613 1/20 0.40
IGF1R P08069 1/20 0.39
KMT2A Q03164 2/20 0.39
CYP2C19 P33261 1/20 0.39
KDM4E B2RXH2 1/20 0.39
ALOX15 P16050 1/20 0.39
MEN1 O00255 1/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2463787 1.00 L3MBTL1 (0.47) L3MBTL1GLAFABP4FABP5PTGS1
SCHEMBL2461228 0.83 KDM4E (0.50) L3MBTL1FABP4FABP5GAAKMT2A
SCHEMBL2461230 0.83 KDM4E (0.50) L3MBTL1FABP4FABP5GAAKMT2A
SCHEMBL34021 0.81 BCHE (0.47) L3MBTL1GLAPTGS1MRGPRX4KLK1
SCHEMBL11571555 0.78 LMNA (0.50) L3MBTL1FABP4FABP5PTGS1KMT2A
SCHEMBL18606582 0.78 L3MBTL1 (0.43) L3MBTL1GLAPTGS1PTGS2MRGPRX4
SCHEMBL9967744 0.78 GABRA1 (0.59) L3MBTL1GLAPTGS1IGF1RKMT2A
SCHEMBL20677720 0.77 TSHR (0.46) L3MBTL1GLAPTGS1PTGS2KMT2A
SCHEMBL7208889 0.77 ALDH1A1 (0.43) L3MBTL1GLAKLK1KLK5CTDSP1
SCHEMBL9825698 0.76 ALDH1A1 (0.52) L3MBTL1GLAKLK1KLK5GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9006496-B2 Method of separating phenolic compounds in salified form RHODIA OPERATIONS (FR) 2015-04-14 US claimed
EP-2300403-B1 METHOD OF SEPARATING PHENOLIC COMPOUNDS IN SALIFIED FORM RHODIA OPERATIONS (FR) 2013-01-23 EP claimed
US-9403745-B2 Method for separating salified phenolic compounds RHODIA OPERATIONS (FR) 2016-08-02 US disclosed
US-20150274625-A1 METHOD FOR SEPARATING SALIFIED PHENOLIC COMPOUNDS SPECIALTY OPERATIONS FRANCE (FR) 2015-10-01 US disclosed
US-9079842-B2 Method for separating salified phenolic compounds RHODIA OPERATIONS (FR) 2015-07-14 US disclosed
US-9006496-B2 Method of separating phenolic compounds in salified form RHODIA OPERATIONS (FR) 2015-04-14 US disclosed
US-20120264982-A1 METHOD FOR SEPARATING SALIFIED PHENOLIC COMPOUNDS RHODIA OPERATIONS (FR) 2012-10-18 US disclosed
US-20110230674-A1 METHOD OF SEPARATING PHENOLIC COMPOUNDS IN SALIFIED FORM RHODIA OPERATIONS (FR) 2011-09-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150274625-A1 METHOD FOR SEPARATING SALIFIED PHENOLIC COMPOUNDS COMT, GRHPR, ME1 L3MBTL1 4421/4885GLA 69/4885FABP4 878/4885
US-20110230674-A1 METHOD OF SEPARATING PHENOLIC COMPOUNDS IN SALIFIED FORM REN, GRHPR, COMT L3MBTL1 3740/4885GLA 194/4885FABP4 707/4885
US-20120264982-A1 METHOD FOR SEPARATING SALIFIED PHENOLIC COMPOUNDS COMT, GRHPR, ME1 L3MBTL1 4421/4885GLA 69/4885FABP4 878/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.