Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | TDO2 | P48775 | 2/20 | 0.34 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | MDM4 | O15151 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL155403 | 0.84 | IDO1 (0.34) | IDO1TDO2IDO2SMN1; SMN2CYP2C19 | |
| SCHEMBL3408983 | 0.84 | KMT2A (0.38) | KMT2AIDO1TDO2IDO2LMNA | |
| SCHEMBL155136 | 0.80 | IDO1 (0.54) | KMT2AIDO1TDO2IDO2PDE4A | |
| SCHEMBL22599783 | 0.77 | KMT2A (0.38) | KMT2AIDO1TDO2IDO2PDE4A | |
| SCHEMBL3402828 | 0.76 | LMNA (0.44) | KMT2ALMNAHSD17B10KDM4EALDH1A1 | |
| SCHEMBL28360028 | 0.75 | L3MBTL1 (0.43) | KMT2ALMNASMN1; SMN2MAPK14KDM4E | |
| SCHEMBL142563 | 0.73 | NTRK1 (0.48) | KMT2AIDO1TDO2IDO2LMNA | |
| SCHEMBL154458 | 0.72 | IDO1 (0.54) | KMT2AIDO1TDO2IDO2PDE4A | |
| SCHEMBL143891 | 0.67 | DNMT1 (0.38) | KMT2AIDO1TDO2IDO2SMN1; SMN2 | |
| SCHEMBL3404195 | 0.66 | IDO1 (0.50) | IDO1TDO2IDO2MDM2MDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940909-B2 | Indicator platform | BIOSYNTH AG (CH) | 2015-01-27 | — | — | US | disclosed |
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| EP-2427431-A1 | NOVEL INDICATOR PLATFORM | Biosynth AG (CH) | 2012-03-14 | — | — | EP | disclosed |
| US-20120058503-A1 | Novel Indicator Platform | BIOSYNTH AG (CH) | 2012-03-08 | — | — | US | disclosed |
| EP-2256103-A1 | Novel indicator platform | Biosynth AG (CH) | 2010-12-01 | — | — | EP | disclosed |
| WO-2010128120-A1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2010-11-11 | — | — | WO | disclosed |