Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LYPLA1 | O75608 | 6/20 | 0.51 |
| ▸ | LYPLA2 | O95372 | 6/20 | 0.51 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PLA2G6 | O60733 | 2/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.36 |
| ▸ | PNLIP | P16233 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 3/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | PRKCG | P05129 | 1/20 | 0.32 |
| ▸ | PRKCB | P05771 | 1/20 | 0.32 |
| ▸ | PRKCH | P24723 | 1/20 | 0.32 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12370961 | 0.77 | LYPLA1 (0.59) | LYPLA1LYPLA2DAGLAPLA2G6PLA2G4A | |
| SCHEMBL12370966 | 0.77 | LYPLA1 (0.52) | LYPLA1LYPLA2DAGLAPLA2G6PLA2G4A | |
| SCHEMBL3409872 | 0.70 | LYPLA1 (0.47) | LYPLA1LYPLA2DAGLAMAPTPLA2G6 | |
| SCHEMBL10555179 | 0.67 | LYPLA1 (0.50) | LYPLA1LYPLA2DAGLACYP1A2CYP2D6 | |
| SCHEMBL716047 | 0.67 | PRKCA (0.43) | DAGLAPRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL8076103 | 0.67 | CYP1A2 (0.69) | CYP1A2CYP2D6MAPTCYP2C9CYP2C19 | |
| SCHEMBL716045 | 0.67 | PRKCA (0.43) | DAGLAPRKCAPRKD3PRKCGPRKCB | |
| SCHEMBL1480323 | 0.66 | — | — | |
| SCHEMBL19514925 | 0.66 | DAGLA (0.59) | LYPLA1LYPLA2DAGLAPLA2G6PLA2G4A | |
| SCHEMBL19514924 | 0.66 | DAGLA (0.59) | LYPLA1LYPLA2DAGLAPLA2G6PLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254574-A1 | BETA-LACTONES AS ANTIBACTERIAL AGENTS | Ludwig-Maximilians-Universität München (DE) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009106211-A1 | BETA-LACTONES AS ANTIBACTERIAL AGENTS | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2009-09-03 | — | — | WO | disclosed |