Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LYPLA1 | O75608 | 5/20 | 0.47 |
| ▸ | LYPLA2 | O95372 | 5/20 | 0.47 |
| ▸ | DAGLA | Q9Y4D2 | 3/20 | 0.38 |
| ▸ | PNLIP | P16233 | 3/20 | 0.35 |
| ▸ | PLA2G6 | O60733 | 2/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.32 |
| ▸ | DAGLB | Q8NCG7 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.31 |
| ▸ | LPL | P06858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LIPC | P11150 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | FASN | P49327 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.31 |
| ▸ | ABHD12 | Q8N2K0 | 1/20 | 0.31 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12370961 | 0.79 | LYPLA1 (0.59) | LYPLA1LYPLA2DAGLAPNLIPPLA2G6 | |
| SCHEMBL15324596 | 0.71 | LYPLA1 (0.40) | LYPLA1LYPLA2 | |
| SCHEMBL15324595 | 0.71 | LYPLA1 (0.40) | LYPLA1LYPLA2 | |
| SCHEMBL12370966 | 0.71 | LYPLA1 (0.52) | LYPLA1LYPLA2DAGLAPNLIPPLA2G6 | |
| SCHEMBL3402991 | 0.70 | LYPLA1 (0.51) | LYPLA1LYPLA2DAGLAPNLIPPLA2G6 | |
| SCHEMBL10555179 | 0.69 | LYPLA1 (0.50) | LYPLA1LYPLA2DAGLAPNLIPMEN1 | |
| SCHEMBL9265419 | 0.63 | DAGLA (0.71) | LYPLA1LYPLA2DAGLAPNLIPCNR1 | |
| SCHEMBL9265416 | 0.63 | DAGLA (0.71) | LYPLA1LYPLA2DAGLAPNLIPCNR1 | |
| SCHEMBL9265410 | 0.63 | DAGLA (0.71) | LYPLA1LYPLA2DAGLAPNLIPCNR1 | |
| SCHEMBL10083462 | 0.63 | DAGLA (0.58) | LYPLA1LYPLA2DAGLAPNLIPPLA2G6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9521845-B2 | Beta-lactones as antibacterial agents | LUDWIG-MAXIMILIANS-UNIVERSITÄT-MÜNCHEN (DE) | 2016-12-20 | — | — | US | disclosed |
| US-20140163094-A1 | BETA-LACTONES AS ANTIBACTERIAL AGENTS | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2014-06-12 | — | — | US | disclosed |
| US-8669283-B2 | Beta-lactones as antibacterial agents | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2014-03-11 | — | — | US | disclosed |
| US-8563598-B2 | — | — | 2013-10-22 | — | — | US | disclosed |
| EP-2254574-A1 | BETA-LACTONES AS ANTIBACTERIAL AGENTS | Ludwig-Maximilians-Universität München (DE) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009106211-A1 | BETA-LACTONES AS ANTIBACTERIAL AGENTS | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2009-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140163094-A1 | BETA-LACTONES AS ANTIBACTERIAL AGENTS | ALG8, PGLS, GLA | LYPLA1 651/4885LYPLA2 1208/4885DAGLA 219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.