SCHEMBL3403624

SCHEMBL3403624

CO[Si](CCn1c(=O)n(CC[Si](OC)(OC)OC)c(=O)n(CC[Si](OC)(OC)OC)c1=O)(OC)OC

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.30
ADORA2A P29274 1/20 0.30
ADORA2B P29275 1/20 0.30
PDE4B Q07343 1/20 0.30
PDE4C Q08493 1/20 0.30
PDE4D Q08499 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12892325 0.92 PDE4A (0.33) PDE4AADORA2AADORA2BPDE4BPDE4C
SCHEMBL17341698 0.90
SCHEMBL155052 0.86 LMNA (0.33) PDE4AADORA2AADORA2BPDE4BPDE4C
SCHEMBL12158561 0.85 CYP3A4 (0.55) PDE4AADORA2AADORA2BPDE4BPDE4C
SCHEMBL12158562 0.85 CYP3A4 (0.55) PDE4AADORA2AADORA2BPDE4BPDE4C
SCHEMBL3402639 0.85 LMNA (0.32) PDE4AADORA2AADORA2BPDE4BPDE4C
SCHEMBL3400000 0.83 LMNA (0.35) PDE4AADORA2AADORA2BPDE4BPDE4C
SCHEMBL3405710 0.83 LMNA (0.35) PDE4AADORA2AADORA2BPDE4BPDE4C
SCHEMBL3402332 0.83 LMNA (0.35) PDE4AADORA2AADORA2BPDE4BPDE4C
SCHEMBL10015809 0.81 PDE4A (0.33) PDE4AADORA2AADORA2BPDE4BPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2638111-B1 FLUID APPLIED SILICONE AIR&WATER BARRIER SYSTEM AND PROCESS THEREOF MOMENTIVE PERFORMANCE MAT INC (US) 2018-06-27 EP claimed
US-20140079887-A1 FLUID APPLIED SILICONE AIR & WATER BARRIER SYSTEM AND PROCESS THEREOF MOMENTIVE PERFORMANCE MATERIALS INC. 2014-03-20 US claimed
US-8513328-B2 Fluid applied silicone air and water barrier system and process thereof MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-08-20 US claimed
US-20130023602-A1 FLUID APPLIED SILICONE AIR & WATER BARRIER SYSTEM AND PROCESS THEREOF MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-01-24 US claimed
EP-0569186-B1 Silicone additive systems GEN ELECTRIC (US) 2000-08-09 EP claimed
US-5756562-A A METHOXY TERMINATED SILANE OR POLYSILOXANE, AN ADHESION PROMOTER AND WATER GENERAL ELECTRIC COMPANY (US) 1998-05-26 US claimed
US-5420196-A Polyacrylate adhesion GENERAL ELECTRIC COMPANY (US) 1995-05-30 US claimed
WO-2023068016-A1 PAINT COMPOSITION, COATED ARTICLE, AND METHOD FOR FORMING CURED FILM 信越化学工業株式会社 2023-04-27 WO disclosed
US-11424482-B2 Nonaqueous electrolyte solution and nonaqueous electrolyte battery using same MITSUBISHI CHEMICAL CORPORATION (JP) 2022-08-23 US disclosed
CN-108948065-B Hydrophilic alkoxysilane-containing isocyanurates 赢创运营有限公司 2022-07-05 CN disclosed
CN-106569388-B Photosensitive resin composition for black matrix and application thereof 奇美实业股份有限公司 2020-12-04 CN disclosed
WO-2020130072-A1 COATING AGENT, COATING FILM, AND LAMINATE DIC株式会社 2020-06-25 WO disclosed
US-20190334208-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY USING SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2019-10-31 US disclosed
EP-0569186-A1 Silicone additive systems GENERAL ELECTRIC COMPANY (US) 1993-11-10 EP disclosed
EP-0520717-A1 Adhesion promoters for room temperature vulcanizable silicone compositions GENERAL ELECTRIC COMPANY (US) 1992-12-30 EP disclosed
US-5175057-A Polyalkoxy terminated polydiorganosiloxane, tin catalyst, polysiloxane fluid with polar groups GENERAL ELECTRIC COMPANY (US) 1992-12-29 US disclosed
EP-0491482-A1 Room temperature vulcanizable silicone compositions having improved low modulus GENERAL ELECTRIC COMPANY (US) 1992-06-24 EP disclosed
EP-0491483-A1 Adhesion promoter system for one-component RTV silicone compositions GENERAL ELECTRIC COMPANY (US) 1992-06-24 EP disclosed
US-4528353-A Adhesion promoters for one-component RTV silicone compositions GENERAL ELECTRIC COMPANY (US) 1985-07-09 US disclosed
US-4483973-A Adhesion promoters for one-component RTV silicone compositions GENERAL ELECTRIC COMPANY (US) 1984-11-20 US disclosed