SCHEMBL3402639

SCHEMBL3402639

CO[Si](CCCCn1c(=O)n(CCCC[Si](OC)(OC)OC)c(=O)n(CCCC[Si](OC)(OC)OC)c1=O)(OC)OC

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
ADORA2B P29275 2/20 0.32
PDE4A P27815 1/20 0.31
ADORA2A P29274 1/20 0.31
PDE4B Q07343 1/20 0.31
PDE4C Q08493 1/20 0.31
PDE4D Q08499 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3402332 0.98 LMNA (0.35) LMNAADORA2BPDE4AADORA2APDE4B
SCHEMBL3400000 0.98 LMNA (0.35) LMNAADORA2BPDE4AADORA2APDE4B
SCHEMBL3405710 0.98 LMNA (0.35) LMNAADORA2BPDE4AADORA2APDE4B
SCHEMBL155052 0.94 LMNA (0.33) LMNAADORA2BPDE4AADORA2APDE4B
SCHEMBL25916982 0.93 LMNA (0.43) LMNAADORA2BPDE4AADORA2APDE4B
SCHEMBL12892325 0.90 PDE4A (0.33) LMNAADORA2BPDE4AADORA2APDE4B
SCHEMBL10015809 0.88 PDE4A (0.33) LMNAADORA2BPDE4AADORA2APDE4B
SCHEMBL9891728 0.86 RGS4 (0.42) LMNAADORA2BPDE4AADORA2APDE4B
SCHEMBL12164889 0.86 RGS4 (0.42) LMNAADORA2BPDE4AADORA2APDE4B
SCHEMBL30417905 0.85 CYP3A4 (0.48) LMNAADORA2BPDE4AADORA2APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7825243-B2 Process for the production of isocyanatosilane and silylisocyanurate MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-11-02 US claimed
EP-1885731-B1 PROCESS FOR THE PRODUCTION OF ISOCYANATOSILANE AND SILYLISOCYANURATE MOMENTIVE PERFORMANCE MAT INC (US) 2009-11-11 EP claimed
EP-1885731-A1 PROCESS FOR THE PRODUCTION OF ISOCYANATOSILANE AND SILYLISOCYANURATE Momentive Performance Materials Inc. (US) 2008-02-13 EP claimed
WO-2006132799-A1 PROCESS FOR THE PRODUCTION OF ISOCYANATOSILANE AND SILYLISOCYANURATE MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2006-12-14 WO claimed
US-20060276644-A1 Process for the production of isocyanatosilane and silylisocyanurate GENERAL ELECTRIC COMPANY 2006-12-07 US claimed
US-7060849-B1 Method for production of isocyanatosilanes GENERAL ELECTRIC COMPANY (US) 2006-06-13 US claimed
EP-2256153-B1 HYDROPHILIC FILM MITSUI CHEMICALS INC (JP) 2014-06-25 EP disclosed
EP-2256153-A1 HYDROPHILIC FILM Mitsui Chemicals, Inc. (JP) 2010-12-01 EP disclosed
US-7825243-B2 Process for the production of isocyanatosilane and silylisocyanurate MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-11-02 US disclosed
EP-1885731-B1 PROCESS FOR THE PRODUCTION OF ISOCYANATOSILANE AND SILYLISOCYANURATE MOMENTIVE PERFORMANCE MAT INC (US) 2009-11-11 EP disclosed
US-20060276644-A1 Process for the production of isocyanatosilane and silylisocyanurate GENERAL ELECTRIC COMPANY 2006-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060276644-A1 Process for the production of isocyanatosilane and silylisocyanurate SI, TST, PCMT1 LMNA 729/4885ADORA2B 4876/4885PDE4A 4868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.