Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3405710 | 1.00 | LMNA (0.35) | LMNAADORA2BTNFPDE4AADORA2A | |
| SCHEMBL3400000 | 1.00 | LMNA (0.35) | LMNAADORA2BTNFPDE4AADORA2A | |
| SCHEMBL3402639 | 0.98 | LMNA (0.32) | LMNAADORA2BPDE4AADORA2APDE4B | |
| SCHEMBL155052 | 0.92 | LMNA (0.33) | LMNAADORA2BTNFPDE4AADORA2A | |
| SCHEMBL25916982 | 0.91 | LMNA (0.43) | LMNAADORA2BTNFPDE4AADORA2A | |
| SCHEMBL12892325 | 0.88 | PDE4A (0.33) | LMNAADORA2BPDE4AADORA2APDE4B | |
| SCHEMBL30417905 | 0.87 | CYP3A4 (0.48) | LMNAADORA2BPDE4AADORA2APDE4B | |
| SCHEMBL10015809 | 0.86 | PDE4A (0.33) | LMNAADORA2BTNFPDE4AADORA2A | |
| SCHEMBL12164889 | 0.85 | RGS4 (0.42) | LMNAADORA2BTNFPDE4AADORA2A | |
| SCHEMBL9891728 | 0.85 | RGS4 (0.42) | LMNAADORA2BTNFPDE4AADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9512034-B2 | Hydrophilic film | MITSUI CHEMICALS, INC. (JP) | 2016-12-06 | — | — | US | disclosed |
| EP-2256153-B1 | HYDROPHILIC FILM | MITSUI CHEMICALS INC (JP) | 2014-06-25 | — | — | EP | disclosed |
| EP-2256153-A1 | HYDROPHILIC FILM | Mitsui Chemicals, Inc. (JP) | 2010-12-01 | — | — | EP | disclosed |