Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1830308 | 0.70 | TDP1 (0.54) | PTGDRPTGDR2TSHRKDM4EALDH1A1 | |
| SCHEMBL342666 | 0.70 | ALDH1A1 (0.46) | PTGDRPTGDR2TSHRGAAKDM4E | |
| SCHEMBL343027 | 0.69 | TSHR (0.36) | TSHRGAAKDM4EALDH1A1CYP3A4 | |
| SCHEMBL571774 | 0.67 | KDM4E (0.32) | PTGDRPTGDR2KDM4ECYP3A4ALOX12 | |
| SCHEMBL1831195 | 0.66 | KDM4E (0.39) | TSHRGAAKDM4EALDH1A1CYP3A4 | |
| SCHEMBL4459273 | 0.65 | KDM4E (0.48) | TSHRGAAKDM4EALDH1A1CYP3A4 | |
| SCHEMBL341900 | 0.64 | LMNA (0.54) | PTGDRPTGDR2TSHRGAAKDM4E | |
| SCHEMBL692544 | 0.64 | KDM4E (0.49) | TSHRGAAKDM4EALDH1A1CYP3A4 | |
| SCHEMBL3404105 | 0.62 | PTGDR2 (0.53) | PTGDRPTGDR2TSHRKDM4EALDH1A1 | |
| SCHEMBL198192 | 0.62 | KDM4E (0.43) | TSHRKDM4EALDH1A1CYP3A4ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2253207-A1 | Substituted phenyl acetic acid esters | Bayer CropScience AG (DE) | 2010-11-24 | — | — | EP | disclosed |
| EP-2216316-A1 | Phenyl acetic acid derivatives | Bayer CropScience Aktiengesellschaft (DE) | 2010-08-11 | — | — | EP | disclosed |
| EP-2216317-A1 | Phenyl acetic acid halogenides | Bayer CropScience AG (DE) | 2010-08-11 | — | — | EP | disclosed |