Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.50 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.47 |
| ▸ | JAK2 | O60674 | 4/20 | 0.46 |
| ▸ | JAK1 | P23458 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3404423 | 1.00 | GPR119 (0.50) | GPR119USP30JAK2JAK1KDM4E | |
| SCHEMBL8354494 | 0.88 | NPY2R (0.46) | MEN1KMT2AALDH1A1 | |
| SCHEMBL27099778 | 0.84 | GPR119 (0.55) | GPR119USP30JAK2JAK1KDM4E | |
| SCHEMBL3407330 | 0.80 | ACHE (0.48) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3407333 | 0.80 | ACHE (0.48) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL14939767 | 0.79 | GPR119 (0.42) | GPR119USP30JAK2JAK1KDM4E | |
| SCHEMBL16577073 | 0.78 | GPR119 (0.61) | GPR119USP30KDM4EPKMMEN1 | |
| SCHEMBL22468809 | 0.78 | MEN1 (0.51) | GPR119MEN1KMT2AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL10360733 | 0.78 | KDM4E (0.42) | KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL239883 | 0.77 | NPY2R (0.65) | GPR119KDM4EPKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2261205-A1 | METHOD OF PRODUCING (S)-3-(1-CYANO-1,1-DIPHENYLMETHYL)-PYRROLIDINE | Kaneka Corporation (JP) | 2010-12-15 | — | — | EP | claimed |
| EP-2261205-A1 | METHOD OF PRODUCING (S)-3-(1-CYANO-1,1-DIPHENYLMETHYL)-PYRROLIDINE | Kaneka Corporation (JP) | 2010-12-15 | — | — | EP | disclosed |