Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3407333 | 1.00 | ACHE (0.48) | ACHEKMT2AMEN1EPHX1L3MBTL3 | |
| SCHEMBL10360085 | 0.88 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL8354494 | 0.82 | NPY2R (0.46) | KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10360083 | 0.81 | NPY2R (0.53) | MGLLNPC1RAB9A | |
| SCHEMBL3404425 | 0.80 | GPR119 (0.50) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL3404423 | 0.80 | GPR119 (0.50) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL10360733 | 0.79 | KDM4E (0.42) | KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL22623975 | 0.77 | ACHE (0.59) | ACHEKMT2AMEN1EPHX1L3MBTL3 | |
| SCHEMBL10360737 | 0.75 | NPY2R (0.58) | MGLLNPC1RAB9A | |
| SCHEMBL13818490 | 0.75 | ATM (0.50) | MEN1L3MBTL1ALDH1A1RAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2261205-A1 | METHOD OF PRODUCING (S)-3-(1-CYANO-1,1-DIPHENYLMETHYL)-PYRROLIDINE | Kaneka Corporation (JP) | 2010-12-15 | — | — | EP | disclosed |